Randomized controlled trial for clinical optimization protocol of Xing-Pi Jie-Yu Recipe in the treatment of mild to moderate depressio
- Conditions
- Depression
- Registration Number
- ITMCTR2000002908
- Lead Sponsor
- Dongfang Hospital of Beijing University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Meet the diagnostic criteria for depression;
2. Meet the criteria for liver stagnation and spleen deficiency syndrome;
3. 17 points 4. Aged 18 to 65 years;
5. Signed informed consent.
1. Patients with bipolar disorder and schizophrenia;
2. People who have used sedative hypnosis and SSRIs antidepressants in the past month;
3. People with drug or alcohol dependence within 1 year;
4. Those with serious history of heart disease, liver, kidney, endocrine, blood and other medical diseases or epilepsy;
5. authors of rapid onset of depression and bidirectional disorder secondary to other mental or physical diseases;
6. abnormal ECG Those who have abnormal laboratory results and have clinical significance;
7. pregnant and lactating women;
8. those with a serious suicidal tendency;
9. baseline and screening comparison, the total score of the Hamilton Depression Scale (HAMD-17) Decrease by 25%;
10. Those without a guardian or who cannot take medicine as directed by a doctor.
Patients who meet any of the above are excluded.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HAMD-17;
- Secondary Outcome Measures
Name Time Method PHQ-15;TCM Syndrome Score;HAMA;PSQI;