Multi-institutional Prospective Registry in Pulmonary Hypertension associated with Respiratory Disease
Not Applicable
Recruiting
- Conditions
- Pulmonary Hypertension Associated with Respiratory Disease
- Registration Number
- JPRN-UMIN000011541
- Lead Sponsor
- Steering Committee for Multi-institutional Prospective Registry in Pulmonary Hypertension associated with Respiratory Disease
- Brief Summary
281 patients with R-PH were included in this study. 43% had mild ventilatory impairment (MVI), 52% had a severe form of PH. 68% received PAH-targeted therapies. In MVI, those treated initially had better survival than patients not treated initially (3-year survival 70.6% vs. 34.2%; P=0.01), and no significant difference was obsereved in severe ventilatory impairment (49.6% vs. 32.1%; P=0.38). Responders to PAH-targeted therapy were more prevalent in the group with MVI.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 281
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who refused this study Under 18 years old
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ung transplantation Worsening of NHYA, Addition of PAH specific drugs, Hospitalization due to PH Prevalence of progression from borderline PH
- Secondary Outcome Measures
Name Time Method iver dysfunction Edema Adverse effects of drugs Pregnancy Hospitalization due to infection and respiratory failure Mechanical ventilation