Prospective surveillance of patients with developing chronic pulmonary thromboembolism and chronic thromboembolic pulmonary hypertension after occurring acute pulmonary thromboembolism
Not Applicable
- Conditions
- acute pulmonary thromboembolism
- Registration Number
- JPRN-UMIN000026437
- Lead Sponsor
- agoya University Graduate School of Medicine, Department of Cardiology
- Brief Summary
Fifty-two patients were enrolled. Two patients(3.8%)developed chronic thromboembolic pulmonary hypertension. A total of 43 patients completed evaluation at 1 year, among whom (74%) had residual thrombi, with a median modified CT obstruction index (mCTOI) of 10.7%. The tricuspid regurgitation pressure gradient 60 mmHg or over and left ventricular end-diastolic dimension at diagnosis were significantly related to mCTOI at 1 year.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
Not provided
Exclusion Criteria
1) contrast medium allergy 2) eGFR lower than 30 mL/min/1.73m2 3) pregnancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The developing risk of chronic pulmonary thromboembolism and chronic thromboembolic pulmonary hypertension after one year ocurring acute pulmonary thromboembolism
- Secondary Outcome Measures
Name Time Method 1) developing risk of chronic pulmonary thromboembolism 2) developing risk of chronic thromboembolic pulmonary hypertension 3) recurrence of symptomatic acute pulmonary embolism 4)all cause death, cardiovascular death, non-cardiovascular death 5) incidence of bleeding 6) comparison of baseline characteristics 7) comparison among the treatments 8) trend of coagulation markers