Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer

Phase 3

Completed

• Conditions: Esophageal Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma; Stage IIA Esophageal Cancer AJCC v7; Stage IIB Esophageal Cancer AJCC v7; Stage IIIA Esophageal Cancer AJCC v7; Stage IB Esophageal Cancer AJCC v7; Stage IIIB Esophageal Cancer AJCC v7
• Interventions: Drug: Carboplatin; Other: Laboratory Biomarker Analysis; Drug: Paclitaxel; Other: Quality-of-Life Assessment; Radiation: Radiation Therapy; Procedure: Therapeutic Conventional Surgery; Biological: Trastuzumab

• Registration Number: NCT01196390
• Lead Sponsor: National Cancer Institute (NCI)

Brief Summary

This randomized phase III trial studies how well radiation therapy, paclitaxel, and carboplatin with or without trastuzumab work in treating patients with esophageal cancer. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Monoclonal antibodies, such as trastuzumab, may interfere with the ability of tumor cells to grow and spread. It is not yet known whether giving radiation therapy and combination chemotherapy together with or without trastuzumab is more effective in treating esophageal cancer.

Detailed Description

PRIMARY OBJECTIVES:

l. To determine if trastuzumab increases disease-free survival when combined with trimodality treatment (radiation plus chemotherapy followed by surgery) for patients with human epidermal growth factor receptor 2 (HER2)-overexpressing esophageal adenocarcinoma.

SECONDARY OBJECTIVES:

I. To evaluate if the addition of trastuzumab to trimodality treatment increases the pathologic complete response rate and overall survival for patients with HER2-overexpressing esophageal adenocarcinoma.

II. To develop a tissue bank of tumor tissue from patients with non-metastatic esophageal adenocarcinoma.

III. To determine molecular correlates of complete pathologic response, disease-free survival, and overall survival for patients with HER2-overexpressing esophageal adenocarcinoma treated with neoadjuvant and maintenance trastuzumab.

IV. To evaluate predictors of cardiotoxicity in patients with esophageal cancer treated with trastuzumab and chemoradiation.

V. To evaluate adverse events associated with the addition of trastuzumab to trimodality treatment for patients with non-metastatic esophageal adenocarcinoma.

PATIENT-REPORTED QUALITY OF LIFE OBJECTIVES:

I. To determine if the addition of trastuzumab to trimodality treatment improves the patient-reported Functional Assessment of Cancer Therapy for Esophageal Cancer (FACT-E) Esophageal Cancer Subscale (ECS) score.

II. To determine if an improvement in the FACT-E ECS score at 6-8 weeks post completion of neoadjuvant chemoradiation correlates with pathologic complete response.

III. To determine if pathologic complete response correlates with the FACT-E ECS score at 1 year and/or 2 years from the start of chemoradiation.

IV. To determine if the addition of trastuzumab to trimodality treatment improves the Swallow Index and Eating Index Subscale scores of the FACT-E.

V. To determine if the addition of trastuzumab to paclitaxel, carboplatin, and radiation impacts quality-adjusted survival.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive trastuzumab intravenously (IV) over 30-90 minutes on days 1, 8, 15, 22, 29, 36, and 57 and paclitaxel IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36. Beginning 21-56 days after surgery, patients receive trastuzumab IV over 30-90 minutes. Treatment repeats every 21 days for 13 courses in the absence of disease progression or unacceptable toxicity.

ARM II: Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive paclitaxel IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36.

Within 5-8 weeks after completion of radiotherapy, all patients undergo surgery.

After completion of study therapy, patients are followed up every 4 months for 2 years and then yearly thereafter.

Study Timeline

• Study First Submitted: 2010-09-04
• Study First Submitted QC: 2010-09-04
• Study First Posted: 2010-09-08
• Study Start: 2011-02-14
• Primary Completion: 2019-12-23
• Results First Submitted: 2021-03-01
• Results First Submitted QC: 2021-04-12
• Results First Posted: 2021-05-04
• Status Verified: 2023-08
• Study Completion: 2023-08-15
• Last Update Submitted: 2023-08-16
• Last Update Posted: 2023-09-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 203

Inclusion Criteria

• Pathologically confirmed primary adenocarcinoma of the esophagus that involves the mid (up to 25 cm), distal, or esophagogastric junction; the cancer may involve the stomach up to 5 cm

• Endoscopy with biopsy

• PRIOR TO STEP 1 REGISTRATION BUT WITHIN 56 DAYS PRIOR TO STEP 2 REGISTRATION

• Intent to submit tissue for central HER2 testing

• Stage T1N1-2, T2-3N0-2, according to the American Joint Committee on Cancer (AJCC) 7th edition staging, based on the following minimum diagnostic work-up:

  • Chest/abdominal/pelvic computed tomography (CT) or whole-body positron emission tomography (PET)/CT (NOTE: if CT is performed at this time point, whole-body PET/CT will be required prior to step 2 registration; PET/CT of skull base to mid-thigh is acceptable) (NOTE: if adenopathy is noted on CT or whole-body PET/CT scan, an endoscopic ultrasound is not required prior to STEP 2 registration as long as adequate tissue has been obtained for central HER2 testing)
  • Patients may have regional adenopathy including para-esophageal, gastric, gastrohepatic and celiac nodes; if celiac adenopathy is present, it must be =< 2 cm
  • Patients with tumors at the level of the carina or above must undergo bronchoscopy to exclude fistula

• Zubrod performance status 0-2

• Absolute neutrophil count (ANC) >= 1,500 cells/mm^3

• Platelets >= 100,000 cells/mm^3

• Hemoglobin >= 8.0 g/dL (note: the use of transfusion or other intervention to achieve hemoglobin [Hgb] >= 8.0 g/dL is acceptable)

• Creatinine =< 2 times upper limit of normal

• Bilirubin =< 1.5 times upper limit of normal

• Aspartate aminotransferase (AST) =< 3.0 times upper limit of normal

• For women of childbearing potential, a negative serum or urine pregnancy test

• Patients must sign a study-specific informed consent prior to study entry

• CONDITIONS FOR PATIENT ELIGIBILITY PRIOR TO STEP 2 REGISTRATION (HER2-POSITIVE PATIENTS ONLY)

• HER2 expressing adenocarcinoma of the esophagus centrally

• Surgical consultation to confirm that patient will be able to undergo curative resection after completion of chemoradiation within 56 days prior to step 2 registration

• Radiation oncology consultation to confirm that disease can be encompassed in a radiotherapy field within 56 days prior to step 2 registration

• Consultation with a medical oncologist within 56 days prior to step 2 registration

• Stage T1N1-2, T2-3N0-2, according to the AJCC 7th edition staging, based upon the following minimum diagnostic work-up:

  • History/physical examination, with documentation of the patient's weight, within 14 days prior to step 2 registration
  • Whole-body PET/CT scan within 56 days prior to step 2 registration (if only CT performed prior to step 1 registration)
  • Endoscopic ultrasound within 56 days prior to step 2 registration, unless the patient is found to have adenopathy per CT or whole-body PET/CT scan
  • Electrocardiogram (EKG) within 56 days prior to step 2 registration
  • Serum creatinine =< 2 x the upper limit or normal within 14 days prior to step 2 registration

• Zubrod performance status 0-2 within 14 days prior to step 2 registration

• For women of childbearing potential, a negative serum pregnancy test within 14 days prior to step 2 registration

• Left ventricular ejection fraction (LVEF) >= institutional lower limit of normal by cardiac echocardiogram (echo) or multi gated acquisition (MUGA) scan within 56 days prior to step 2 registration

• Women of childbearing potential and sexually active male participants must agree to practice adequate contraception while on study and for at least 60 days following the last dose of chemotherapy or trastuzumab

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Exclusion Criteria

• Patients with cervical esophageal carcinoma

• Patients with T1N0 disease, T4 disease, and proximal esophageal cancers (15-24 cm)

• Prior systemic chemotherapy for esophageal cancer; note that prior chemotherapy for a different cancer is allowable

• Prior radiation therapy for esophageal cancer or prior chest radiotherapy

• Prior anthracycline or taxane

• Evidence of tracheoesophageal fistula or invasion into the trachea or major bronchi

• Prior invasive malignancy (except non-melanomatous skin cancer), unless disease free for a minimum of 2 years (e.g., carcinoma in situ of the breast, oral cavity, or cervix are permissible)

• Medical contraindications to esophagectomy

• Prior therapy with any agent targeting the HER2 pathway or human epidermal growth factor receptor 1 (HER1) (epidermal growth factor receptor [EGFR]) pathway

• Prior therapy with trastuzumab

• Prior allergic reaction to the study drugs involved in this protocol or to a monoclonal antibody

• Previous history of congestive heart failure

• Severe, active comorbidity, defined as follows:

  • Unstable angina in the last 6 months
  • Transmural myocardial infarction within the last 6 months
  • Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration
  • Acquired immune deficiency syndrome (AIDS) based upon current Centers for Disease Control and Prevention (CDC) definition; note, however that human immunodeficiency virus (HIV) testing is not required for entry into this protocol; protocol-specific requirements may also exclude immunocompromised patients

• Pregnant or nursing women or women of childbearing potential and men who are sexually active and not willing/able to use medically acceptable forms of contraception

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Arm I (radiotherapy, chemotherapy, trastuzumab)	Laboratory Biomarker Analysis	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive trastuzumab IV over 30-90 minutes on days 1, 8, 15, 22, 29, 36, and 57 and paclitaxel intravenously IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36. Beginning 21-56 days after surgery, patients receive trastuzumab IV over 30-90 minutes. Treatment repeats every 21 days for 13 courses in the absence of disease progression or unacceptable toxicity.
Arm I (radiotherapy, chemotherapy, trastuzumab)	Quality-of-Life Assessment	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive trastuzumab IV over 30-90 minutes on days 1, 8, 15, 22, 29, 36, and 57 and paclitaxel intravenously IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36. Beginning 21-56 days after surgery, patients receive trastuzumab IV over 30-90 minutes. Treatment repeats every 21 days for 13 courses in the absence of disease progression or unacceptable toxicity.
Arm I (radiotherapy, chemotherapy, trastuzumab)	Radiation Therapy	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive trastuzumab IV over 30-90 minutes on days 1, 8, 15, 22, 29, 36, and 57 and paclitaxel intravenously IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36. Beginning 21-56 days after surgery, patients receive trastuzumab IV over 30-90 minutes. Treatment repeats every 21 days for 13 courses in the absence of disease progression or unacceptable toxicity.
Arm I (radiotherapy, chemotherapy, trastuzumab)	Therapeutic Conventional Surgery	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive trastuzumab IV over 30-90 minutes on days 1, 8, 15, 22, 29, 36, and 57 and paclitaxel intravenously IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36. Beginning 21-56 days after surgery, patients receive trastuzumab IV over 30-90 minutes. Treatment repeats every 21 days for 13 courses in the absence of disease progression or unacceptable toxicity.
Arm I (radiotherapy, chemotherapy, trastuzumab)	Trastuzumab	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive trastuzumab IV over 30-90 minutes on days 1, 8, 15, 22, 29, 36, and 57 and paclitaxel intravenously IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36. Beginning 21-56 days after surgery, patients receive trastuzumab IV over 30-90 minutes. Treatment repeats every 21 days for 13 courses in the absence of disease progression or unacceptable toxicity.
Arm II (radiotherapy and chemotherapy)	Carboplatin	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive paclitaxel IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36.
Arm II (radiotherapy and chemotherapy)	Laboratory Biomarker Analysis	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive paclitaxel IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36.
Arm II (radiotherapy and chemotherapy)	Paclitaxel	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive paclitaxel IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36.
Arm II (radiotherapy and chemotherapy)	Quality-of-Life Assessment	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive paclitaxel IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36.
Arm II (radiotherapy and chemotherapy)	Radiation Therapy	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive paclitaxel IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36.
Arm II (radiotherapy and chemotherapy)	Therapeutic Conventional Surgery	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive paclitaxel IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36.
Arm I (radiotherapy, chemotherapy, trastuzumab)	Carboplatin	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive trastuzumab IV over 30-90 minutes on days 1, 8, 15, 22, 29, 36, and 57 and paclitaxel intravenously IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36. Beginning 21-56 days after surgery, patients receive trastuzumab IV over 30-90 minutes. Treatment repeats every 21 days for 13 courses in the absence of disease progression or unacceptable toxicity.
Arm I (radiotherapy, chemotherapy, trastuzumab)	Paclitaxel	Patients undergo radiotherapy once daily 5 days a week for 5.5 weeks. Patients also receive trastuzumab IV over 30-90 minutes on days 1, 8, 15, 22, 29, 36, and 57 and paclitaxel intravenously IV over 60 minutes and carboplatin IV over 30-60 minutes on days 1, 8, 15, 22, 29, and 36. Beginning 21-56 days after surgery, patients receive trastuzumab IV over 30-90 minutes. Treatment repeats every 21 days for 13 courses in the absence of disease progression or unacceptable toxicity.

Primary Outcome Measures

Name	Time	Method
Disease-free Survival (DFS)	From randomization to last follow-up. Maximum follow-up at time of analysis was 8.0 years.	A disease event is defined as local/regional persistence or recurrence of the cancer under study, distant metastases, a new second primary cancer, or death due to any cause. Participants undergoing surgery who had an R2 resection and participants not undergoing surgery who had a positive endoscopic biopsy or no biopsy at all were considered to have local persistence of disease. Disease-free survival time is defined as time from randomization to the date of first disease event or last known follow-up (censored). Rates are estimated by the Kaplan-Meier method. Analysis was to occur after 162 events were reported.

Secondary Outcome Measures

Name	Time	Method
Overall Survival	From randomization to last follow-up. Maximum follow-up at time of analysis was 8 years.	Overall survival time is defined as time from randomization to the date of death from any cause or last known follow-up (censored). Rates are estimated by the Kaplan-Meier method. Analysis occurred after 109 deaths were reported.
Number of Participants With Any Cardiac Adverse Events Regardless of Attribution	From randomization to last follow-up. Maximum follow-up at time of analysis was 8 years.	Common Terminology Criteria for Adverse Events (version 4.0) grades adverse event (AE) severity from 1=mild to 5=death. Logistic regression was used to evaluate treatment arm, clinical tumor stage (T stage), Zubrod Performance Status, gender, presence of adenopathy, and age as possible predictors of cardiac adverse events. Results of the final model are reported in the statistical analysis section. Summary adverse event data is provided in this outcome measure; see Adverse Events Module for specific adverse event data.
Percentage of Participants With Pathologic Complete Response at Surgery	At the time of surgery, 5-8 weeks after completion of radiation therapy.	Pathologic Complete Response (pCR) is evaluated after surgery and is based on the pathology review of the submitted surgical specimen. Pathologic Complete Response occurs if the pathologist determines that the resected esophageal specimen, accompanying lymph nodes, and surgical margins are all free of tumor.
Percentage of Patients With Improvement in the Functional Assessment of Cancer Therapy - Esophagus (FACT-E) Esophageal Cancer Subscale (ECS) Subscale After Treatment	Baseline, 6-8 weeks after end of radiation therapy (approximately 11.5-13.5 weeks from treatment start), 1 and 2 years from treatment start	The ECS is a 17-item self-report instrument designed to measure multidimensional quality of life in patients with esophagus cancer with a total score ranging from 0-68. It is to be administered with the Functional Assessment of Cancer Therapy - General (FACT-G). A higher score indicates better QOL. Improvement is defined as an increase from the baseline score of at least 5 points.
Quality-adjusted Survival	From randomization to last follow-up. Maximum follow-up at time of primary outcome measure analysis was 8 years.
Molecular Correlates of Efficacy	From randomization to last follow-up. Maximum follow-up at time of primary outcome measure analysis was 8 years.
Frequency of Highest Grade Adverse Event Per Participant	From randomization to last follow-up. Maximum follow-up at time of analysis was 8 years.	Common Terminology Criteria for Adverse Events (version 4.0 before 4-1-2018; then version 5.0) grades adverse event severity from 1=mild to 5=death. Summary data provided is in this outcome measure; see Adverse Events Module for specific adverse event data.

Trial Locations

Locations (631)

University of Maryland/Greenebaum Cancer Center; 🇺🇸 Baltimore, Maryland, United States

Weiss Memorial Hospital; 🇺🇸 Chicago, Illinois, United States

Massachusetts General Hospital Cancer Center; 🇺🇸 Boston, Massachusetts, United States

University of Washington Medical Center - Montlake; 🇺🇸 Seattle, Washington, United States

FHCC South Lake Union; 🇺🇸 Seattle, Washington, United States

Miami Cancer Institute; 🇺🇸 Miami, Florida, United States

Radiation Oncology Centers of Nevada Southeast; 🇺🇸 Las Vegas, Nevada, United States

Cancer and Blood Specialists-Tenaya; 🇺🇸 Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Northwest; 🇺🇸 Las Vegas, Nevada, United States

GenesisCare USA - Fort Apache; 🇺🇸 Las Vegas, Nevada, United States

Nevada Cancer Research Foundation NCORP; 🇺🇸 Las Vegas, Nevada, United States

Oncology Hematology Care Inc-Mercy West; 🇺🇸 Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Kenwood; 🇺🇸 Cincinnati, Ohio, United States

Utah Cancer Specialists-Salt Lake City; 🇺🇸 Salt Lake City, Utah, United States

LDS Hospital; 🇺🇸 Salt Lake City, Utah, United States

University of Kansas Cancer Center-West; 🇺🇸 Kansas City, Kansas, United States

University of Kansas Cancer Center-Overland Park; 🇺🇸 Overland Park, Kansas, United States

Welch Cancer Center; 🇺🇸 Sheridan, Wyoming, United States

Kansas City NCI Community Oncology Research Program; 🇺🇸 Prairie Village, Kansas, United States

Rocky Mountain Oncology; 🇺🇸 Casper, Wyoming, United States

Boston Medical Center; 🇺🇸 Boston, Massachusetts, United States

University of Mississippi Medical Center; 🇺🇸 Jackson, Mississippi, United States

Washington University School of Medicine; 🇺🇸 Saint Louis, Missouri, United States

California Pacific Medical Center-Pacific Campus; 🇺🇸 San Francisco, California, United States

Mayo Clinic Hospital in Arizona; 🇺🇸 Phoenix, Arizona, United States

Ascension Saint John Hospital; 🇺🇸 Detroit, Michigan, United States

University of Oklahoma Health Sciences Center; 🇺🇸 Oklahoma City, Oklahoma, United States

Porter Adventist Hospital; 🇺🇸 Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One; 🇺🇸 Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown; 🇺🇸 Denver, Colorado, United States

SCL Health Saint Joseph Hospital; 🇺🇸 Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose; 🇺🇸 Denver, Colorado, United States

Rose Medical Center; 🇺🇸 Denver, Colorado, United States

Western States Cancer Research NCORP; 🇺🇸 Denver, Colorado, United States

Providence Portland Medical Center; 🇺🇸 Portland, Oregon, United States

Sutter Cancer Centers Radiation Oncology Services-Auburn; 🇺🇸 Auburn, California, United States

Providence Saint Joseph Medical Center/Disney Family Cancer Center; 🇺🇸 Burbank, California, United States

Mills-Peninsula Medical Center; 🇺🇸 Burlingame, California, United States

Kaiser Permanente-Fremont; 🇺🇸 Fremont, California, United States

Fresno Cancer Center; 🇺🇸 Fresno, California, United States

Contra Costa Regional Medical Center; 🇺🇸 Martinez, California, United States

Highland General Hospital; 🇺🇸 Oakland, California, United States

Hematology and Oncology Associates-Oakland; 🇺🇸 Oakland, California, United States

Kaiser Permanente-Richmond; 🇺🇸 Richmond, California, United States

Kaiser Permanente-Oakland; 🇺🇸 Oakland, California, United States

Kaiser Permanente-Modesto; 🇺🇸 Modesto, California, United States

Bay Area Tumor Institute; 🇺🇸 Oakland, California, United States

Kaiser Permanente Oakland-Broadway; 🇺🇸 Oakland, California, United States

Sutter Cancer Research Consortium; 🇺🇸 Novato, California, United States

El Camino Hospital; 🇺🇸 Mountain View, California, United States

Kaiser Permanente-San Francisco; 🇺🇸 San Francisco, California, United States

Palo Alto Medical Foundation Health Care; 🇺🇸 Palo Alto, California, United States

The Permanente Medical Group-Roseville Radiation Oncology; 🇺🇸 Roseville, California, United States

Christiana Care Health System-Wilmington Hospital; 🇺🇸 Wilmington, Delaware, United States

Saint Helena Hospital; 🇺🇸 Saint Helena, California, United States

AdventHealth Kissimmee; 🇺🇸 Kissimmee, Florida, United States

Delaware Clinical and Laboratory Physicians PA; 🇺🇸 Newark, Delaware, United States

Christiana Care Health System-Christiana Hospital; 🇺🇸 Newark, Delaware, United States

Kaiser Permanente Medical Center - Santa Clara; 🇺🇸 Santa Clara, California, United States

Kaiser Permanente-Vallejo; 🇺🇸 Vallejo, California, United States

Sutter Solano Medical Center/Cancer Center; 🇺🇸 Vallejo, California, United States

Saint Anthony Hospital; 🇺🇸 Lakewood, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge; 🇺🇸 Lone Tree, Colorado, United States

Sky Ridge Medical Center; 🇺🇸 Lone Tree, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood; 🇺🇸 Lakewood, Colorado, United States

Saint Mary Corwin Medical Center; 🇺🇸 Pueblo, Colorado, United States

Mountain Blue Cancer Care Center - Swedish; 🇺🇸 Englewood, Colorado, United States

Smilow Cancer Hospital Care Center at Saint Francis; 🇺🇸 Hartford, Connecticut, United States

Poudre Valley Hospital; 🇺🇸 Fort Collins, Colorado, United States

Rocky Mountain Cancer Centers-Littleton; 🇺🇸 Littleton, Colorado, United States

Hartford Hospital; 🇺🇸 Hartford, Connecticut, United States

Helen F Graham Cancer Center; 🇺🇸 Newark, Delaware, United States

Longmont United Hospital; 🇺🇸 Longmont, Colorado, United States

Midstate Medical Center; 🇺🇸 Meriden, Connecticut, United States

AdventHealth Winter Park; 🇺🇸 Winter Park, Florida, United States

Memorial Health University Medical Center; 🇺🇸 Savannah, Georgia, United States

Grady Health System; 🇺🇸 Atlanta, Georgia, United States

Centralia Oncology Clinic; 🇺🇸 Centralia, Illinois, United States

Crossroads Cancer Center; 🇺🇸 Effingham, Illinois, United States

Northeast Georgia Medical Center-Gainesville; 🇺🇸 Gainesville, Georgia, United States

Presence Saint Mary's Hospital; 🇺🇸 Kankakee, Illinois, United States

William Backus Hospital; 🇺🇸 Norwich, Connecticut, United States

AdventHealth Altamonte; 🇺🇸 Altamonte Springs, Florida, United States

Robert and Carol Weissman Cancer Center at Martin Health; 🇺🇸 Stuart, Florida, United States

Northwestern University; 🇺🇸 Chicago, Illinois, United States

University of Illinois; 🇺🇸 Chicago, Illinois, United States

Ingalls Memorial Hospital; 🇺🇸 Harvey, Illinois, United States

Saint Joseph Regional Medical Center; 🇺🇸 Lewiston, Idaho, United States

Memorial Hospital of Carbondale; 🇺🇸 Carbondale, Illinois, United States

Porubcin, Michael MD (UIA Investigator); 🇺🇸 Moline, Illinois, United States

Saint Alphonsus Cancer Care Center-Boise; 🇺🇸 Boise, Idaho, United States

Northwest Community Hospital; 🇺🇸 Arlington Heights, Illinois, United States

Garneau, Stewart C MD (UIA Investigator); 🇺🇸 Moline, Illinois, United States

Spector, David MD (UIA Investigator); 🇺🇸 Moline, Illinois, United States

Parkview Hospital Randallia; 🇺🇸 Fort Wayne, Indiana, United States

Advocate Christ Medical Center; 🇺🇸 Oak Lawn, Illinois, United States

Community Howard Regional Health; 🇺🇸 Kokomo, Indiana, United States

Radiation Oncology Associates PC; 🇺🇸 Fort Wayne, Indiana, United States

Franciscan Health Indianapolis; 🇺🇸 Indianapolis, Indiana, United States

Menorah Medical Center; 🇺🇸 Overland Park, Kansas, United States

IU Health Ball Memorial Hospital; 🇺🇸 Muncie, Indiana, United States

Michiana Hematology Oncology PC-Plymouth; 🇺🇸 Plymouth, Indiana, United States

Memorial Hospital of South Bend; 🇺🇸 South Bend, Indiana, United States

Reid Health; 🇺🇸 Richmond, Indiana, United States

University of Iowa/Holden Comprehensive Cancer Center; 🇺🇸 Iowa City, Iowa, United States

Mercy Cancer Center-West Lakes; 🇺🇸 Clive, Iowa, United States

Oncology Associates at Mercy Medical Center; 🇺🇸 Cedar Rapids, Iowa, United States

McFarland Clinic - Boone; 🇺🇸 Boone, Iowa, United States

McFarland Clinic - Ames; 🇺🇸 Ames, Iowa, United States

Dana-Farber/Brigham and Women's Cancer Center at Milford Regional; 🇺🇸 Milford, Massachusetts, United States

Saint Luke's Regional Medical Center; 🇺🇸 Sioux City, Iowa, United States

University of Kansas Cancer Center; 🇺🇸 Kansas City, Kansas, United States

Saint Luke's South Hospital; 🇺🇸 Overland Park, Kansas, United States

TidalHealth Peninsula Regional; 🇺🇸 Salisbury, Maryland, United States

Hickman Cancer Center; 🇺🇸 Adrian, Michigan, United States

Essentia Health Cancer Center; 🇺🇸 Duluth, Minnesota, United States

Essentia Health Saint Mary's Medical Center; 🇺🇸 Duluth, Minnesota, United States

Henry Ford Hospital; 🇺🇸 Detroit, Michigan, United States

Trinity Health Saint Mary Mercy Livonia Hospital; 🇺🇸 Livonia, Michigan, United States

William Beaumont Hospital-Royal Oak; 🇺🇸 Royal Oak, Michigan, United States

Mercy Memorial Hospital; 🇺🇸 Monroe, Michigan, United States

Lakeland Hospital Niles; 🇺🇸 Niles, Michigan, United States

Ascension Providence Hospitals - Novi; 🇺🇸 Novi, Michigan, United States

Miller-Dwan Hospital; 🇺🇸 Duluth, Minnesota, United States

Abbott-Northwestern Hospital; 🇺🇸 Minneapolis, Minnesota, United States

United Hospital; 🇺🇸 Saint Paul, Minnesota, United States

Rice Memorial Hospital; 🇺🇸 Willmar, Minnesota, United States

Fairview Southdale Hospital; 🇺🇸 Edina, Minnesota, United States

Singing River Hospital; 🇺🇸 Pascagoula, Mississippi, United States

Saint Luke's Hospital; 🇺🇸 Chesterfield, Missouri, United States

North Memorial Medical Health Center; 🇺🇸 Robbinsdale, Minnesota, United States

Hennepin County Medical Center; 🇺🇸 Minneapolis, Minnesota, United States

Regions Hospital; 🇺🇸 Saint Paul, Minnesota, United States

Metro Minnesota Community Oncology Research Consortium; 🇺🇸 Saint Louis Park, Minnesota, United States

Central Care Cancer Center - Bolivar; 🇺🇸 Bolivar, Missouri, United States

Montana Cancer Consortium NCORP; 🇺🇸 Billings, Montana, United States

Freeman Health System; 🇺🇸 Joplin, Missouri, United States

Comprehensive Cancer Centers of Nevada - Henderson; 🇺🇸 Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Southeast Henderson; 🇺🇸 Henderson, Nevada, United States

Benefis Healthcare- Sletten Cancer Institute; 🇺🇸 Great Falls, Montana, United States

Delbert Day Cancer Institute at PCRMC; 🇺🇸 Rolla, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology; 🇺🇸 Rolla, Missouri, United States

Saint Luke's East - Lee's Summit; 🇺🇸 Lee's Summit, Missouri, United States

CHI Health Saint Francis; 🇺🇸 Grand Island, Nebraska, United States

Liberty Radiation Oncology Center; 🇺🇸 Liberty, Missouri, United States

Missouri Baptist Sullivan Hospital; 🇺🇸 Sullivan, Missouri, United States

Missouri Baptist Outpatient Center-Sunset Hills; 🇺🇸 Sunset Hills, Missouri, United States

Mercy Hospital Springfield; 🇺🇸 Springfield, Missouri, United States

Billings Clinic Cancer Center; 🇺🇸 Billings, Montana, United States

Kalispell Regional Medical Center; 🇺🇸 Kalispell, Montana, United States

CoxHealth South Hospital; 🇺🇸 Springfield, Missouri, United States

GenesisCare USA - Henderson; 🇺🇸 Henderson, Nevada, United States

Radiation Oncology Centers of Nevada Central; 🇺🇸 Las Vegas, Nevada, United States

GenesisCare USA - Vegas Tenaya; 🇺🇸 Las Vegas, Nevada, United States

Las Vegas Cancer Center-Henderson; 🇺🇸 Henderson, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway; 🇺🇸 Las Vegas, Nevada, United States

Cancer Therapy and Integrative Medicine; 🇺🇸 Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-San Martin; 🇺🇸 Las Vegas, Nevada, United States

Cooper Hospital University Medical Center; 🇺🇸 Camden, New Jersey, United States

Rutgers New Jersey Medical School; 🇺🇸 Newark, New Jersey, United States

Virtua Voorhees; 🇺🇸 Voorhees, New Jersey, United States

Memorial Sloan Kettering Commack; 🇺🇸 Commack, New York, United States

Mount Sinai West; 🇺🇸 New York, New York, United States

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center; 🇺🇸 New York, New York, United States

Atrium Health Cabarrus/LCI-Concord; 🇺🇸 Concord, North Carolina, United States

Summa Health System - Akron Campus; 🇺🇸 Akron, Ohio, United States

Cleveland Clinic Akron General; 🇺🇸 Akron, Ohio, United States

UNC Rex Healthcare; 🇺🇸 Raleigh, North Carolina, United States

UHHS-Chagrin Highlands Medical Center; 🇺🇸 Beachwood, Ohio, United States

Trinity Cancer Care Center; 🇺🇸 Minot, North Dakota, United States

Essentia Health Cancer Center-South University Clinic; 🇺🇸 Fargo, North Dakota, United States

Summa Health System - Barberton Campus; 🇺🇸 Barberton, Ohio, United States

Geauga Hospital; 🇺🇸 Chardon, Ohio, United States

Toledo Clinic Cancer Centers-Bowling Green; 🇺🇸 Bowling Green, Ohio, United States

ProMedica Flower Hospital; 🇺🇸 Sylvania, Ohio, United States

Mercy Hospital of Tiffin; 🇺🇸 Tiffin, Ohio, United States

Case Western Reserve University; 🇺🇸 Cleveland, Ohio, United States

Oncology Hematology Care Inc-Blue Ash; 🇺🇸 Cincinnati, Ohio, United States

MetroHealth Medical Center; 🇺🇸 Cleveland, Ohio, United States

Dayton NCI Community Oncology Research Program; 🇺🇸 Dayton, Ohio, United States

Blanchard Valley Hospital; 🇺🇸 Findlay, Ohio, United States

Lima Memorial Hospital; 🇺🇸 Lima, Ohio, United States

Fairfield Medical Center; 🇺🇸 Lancaster, Ohio, United States

Knox Community Hospital; 🇺🇸 Mount Vernon, Ohio, United States

Saint Vincent Mercy Medical Center; 🇺🇸 Toledo, Ohio, United States

Delaware County Memorial Hospital; 🇺🇸 Drexel Hill, Pennsylvania, United States

Toledo Clinic Cancer Centers-Toledo; 🇺🇸 Toledo, Ohio, United States

UPMC Jameson; 🇺🇸 New Castle, Pennsylvania, United States

UPMC-Presbyterian Hospital; 🇺🇸 Pittsburgh, Pennsylvania, United States

Radiation Oncology Associates Incorporated; 🇺🇸 Providence, Rhode Island, United States

Prisma Health Cancer Institute - Spartanburg; 🇺🇸 Boiling Springs, South Carolina, United States

Greenville Health System Cancer Institute-Andrews; 🇺🇸 Greenville, South Carolina, United States

Wellmont Holston Valley Hospital and Medical Center; 🇺🇸 Kingsport, Tennessee, United States

Saint George Regional Medical Center; 🇺🇸 Saint George, Utah, United States

MultiCare Good Samaritan Hospital; 🇺🇸 Puyallup, Washington, United States

Swedish Medical Center-First Hill; 🇺🇸 Seattle, Washington, United States

Aurora Cancer Care-Grafton; 🇺🇸 Grafton, Wisconsin, United States

Marshfield Medical Center - Weston; 🇺🇸 Weston, Wisconsin, United States

University of Alabama at Birmingham Cancer Center; 🇺🇸 Birmingham, Alabama, United States

The Kirklin Clinic at Acton Road; 🇺🇸 Birmingham, Alabama, United States

Capital Region Southwest Campus; 🇺🇸 Jefferson City, Missouri, United States

Saint Louis Cancer and Breast Institute-South City; 🇺🇸 Saint Louis, Missouri, United States

University of Kansas Cancer Center - Lee's Summit; 🇺🇸 Lee's Summit, Missouri, United States

Glens Falls Hospital; 🇺🇸 Glens Falls, New York, United States

Park Nicollet Clinic - Saint Louis Park; 🇺🇸 Saint Louis Park, Minnesota, United States

Littleton Adventist Hospital; 🇺🇸 Littleton, Colorado, United States

Rocky Mountain Cancer Centers-Longmont; 🇺🇸 Longmont, Colorado, United States

North Suburban Medical Center; 🇺🇸 Thornton, Colorado, United States

Parker Adventist Hospital; 🇺🇸 Parker, Colorado, United States

Rocky Mountain Cancer Centers - Pueblo; 🇺🇸 Pueblo, Colorado, United States

Rocky Mountain Cancer Centers-Thornton; 🇺🇸 Thornton, Colorado, United States

SCL Health Lutheran Medical Center; 🇺🇸 Wheat Ridge, Colorado, United States

Rocky Mountain Cancer Centers-Parker; 🇺🇸 Parker, Colorado, United States

Eastern Connecticut Hematology and Oncology Associates; 🇺🇸 Norwich, Connecticut, United States

Mayo Clinic in Rochester; 🇺🇸 Rochester, Minnesota, United States

Alegent Health Lakeside Hospital; 🇺🇸 Omaha, Nebraska, United States

Nebraska Methodist Hospital; 🇺🇸 Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center; 🇺🇸 Omaha, Nebraska, United States

Aurora Saint Luke's Medical Center; 🇺🇸 Milwaukee, Wisconsin, United States

Medical College of Wisconsin; 🇺🇸 Milwaukee, Wisconsin, United States

Aurora Sinai Medical Center; 🇺🇸 Milwaukee, Wisconsin, United States

Henry Ford West Bloomfield Hospital; 🇺🇸 West Bloomfield, Michigan, United States

Good Samaritan Regional Health Center; 🇺🇸 Mount Vernon, Illinois, United States

Mary Greeley Medical Center; 🇺🇸 Ames, Iowa, United States

Mercy Medical Center-West Lakes; 🇺🇸 West Des Moines, Iowa, United States

McFarland Clinic - Jefferson; 🇺🇸 Jefferson, Iowa, United States

Cancer and Blood Specialists-Shadow; 🇺🇸 Las Vegas, Nevada, United States

GenesisCare USA - Las Vegas; 🇺🇸 Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada-Summerlin; 🇺🇸 Las Vegas, Nevada, United States

Las Vegas Cancer Center-Medical Center; 🇺🇸 Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills; 🇺🇸 Las Vegas, Nevada, United States

UC Irvine Health/Chao Family Comprehensive Cancer Center; 🇺🇸 Orange, California, United States

CHI Health Good Samaritan; 🇺🇸 Kearney, Nebraska, United States

Emory University Hospital/Winship Cancer Institute; 🇺🇸 Atlanta, Georgia, United States

USC / Norris Comprehensive Cancer Center; 🇺🇸 Los Angeles, California, United States

Providence Hospital; 🇺🇸 Mobile, Alabama, United States

IU Health La Porte Hospital; 🇺🇸 La Porte, Indiana, United States

Doctors Medical Center- JC Robinson Regional Cancer Center; 🇺🇸 San Pablo, California, United States

The Medical Center of Aurora; 🇺🇸 Aurora, Colorado, United States

Ridgeview Medical Center; 🇺🇸 Waconia, Minnesota, United States

Piedmont Hospital; 🇺🇸 Atlanta, Georgia, United States

Mac Neal Hospital; 🇺🇸 Berwyn, Illinois, United States

Piedmont Fayette Hospital; 🇺🇸 Fayetteville, Georgia, United States

Michiana Hematology Oncology PC-Westville; 🇺🇸 Westville, Indiana, United States

Green Bay Oncology - Escanaba; 🇺🇸 Escanaba, Michigan, United States

Mercy Hospital; 🇺🇸 Coon Rapids, Minnesota, United States

Bixby Medical Center; 🇺🇸 Adrian, Michigan, United States

Saint John's Hospital - Healtheast; 🇺🇸 Maplewood, Minnesota, United States

Green Bay Oncology - Iron Mountain; 🇺🇸 Iron Mountain, Michigan, United States

William Beaumont Hospital - Troy; 🇺🇸 Troy, Michigan, United States

Saint John Macomb-Oakland Hospital; 🇺🇸 Warren, Michigan, United States

Minnesota Oncology Hematology PA-Maplewood; 🇺🇸 Maplewood, Minnesota, United States

Siteman Cancer Center-South County; 🇺🇸 Saint Louis, Missouri, United States

Missouri Baptist Medical Center; 🇺🇸 Saint Louis, Missouri, United States

Saint Francis Medical Center; 🇺🇸 Cape Girardeau, Missouri, United States

Heartland Regional Medical Center; 🇺🇸 Saint Joseph, Missouri, United States

University Medical Center of Southern Nevada; 🇺🇸 Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Tenaya; 🇺🇸 Las Vegas, Nevada, United States

Morristown Medical Center; 🇺🇸 Morristown, New Jersey, United States

Renown Regional Medical Center; 🇺🇸 Reno, Nevada, United States

Comprehensive Cancer Centers of Nevada; 🇺🇸 Las Vegas, Nevada, United States

OptumCare Cancer Care at Fort Apache; 🇺🇸 Las Vegas, Nevada, United States

MD Anderson Cancer Center at Cooper-Voorhees; 🇺🇸 Voorhees, New Jersey, United States

Carolinas Medical Center/Levine Cancer Institute; 🇺🇸 Charlotte, North Carolina, United States

Atrium Health Pineville/LCI-Pineville; 🇺🇸 Charlotte, North Carolina, United States

Atrium Medical Center-Middletown Regional Hospital; 🇺🇸 Franklin, Ohio, United States

Mercy Cancer Center-Elyria; 🇺🇸 Elyria, Ohio, United States

Matthews Radiation Oncology Center; 🇺🇸 Matthews, North Carolina, United States

Alaska Women's Cancer Care; 🇺🇸 Anchorage, Alaska, United States

Katmai Oncology Group; 🇺🇸 Anchorage, Alaska, United States

Anchorage Oncology Centre; 🇺🇸 Anchorage, Alaska, United States

Alaska Breast Care and Surgery LLC; 🇺🇸 Anchorage, Alaska, United States

Providence Alaska Medical Center; 🇺🇸 Anchorage, Alaska, United States

Mayo Clinic in Arizona; 🇺🇸 Scottsdale, Arizona, United States

Kaiser Permanente-Deer Valley Medical Center; 🇺🇸 Antioch, California, United States

Alta Bates Summit Medical Center-Herrick Campus; 🇺🇸 Berkeley, California, United States

Enloe Medical Center; 🇺🇸 Chico, California, United States

East Bay Radiation Oncology Center; 🇺🇸 Castro Valley, California, United States

Mercy San Juan Medical Center; 🇺🇸 Carmichael, California, United States

City of Hope Comprehensive Cancer Center; 🇺🇸 Duarte, California, United States

Epic Care-Dublin; 🇺🇸 Dublin, California, United States

Bay Area Breast Surgeons Inc; 🇺🇸 Emeryville, California, United States

Epic Care Partners in Cancer Care; 🇺🇸 Emeryville, California, United States

Kaiser Permanente-Fresno; 🇺🇸 Fresno, California, United States

Marin General Hospital; 🇺🇸 Greenbrae, California, United States

Los Angeles County-USC Medical Center; 🇺🇸 Los Angeles, California, United States

Cedars Sinai Medical Center; 🇺🇸 Los Angeles, California, United States

Memorial Medical Center; 🇺🇸 Springfield, Illinois, United States

Alta Bates Summit Medical Center - Summit Campus; 🇺🇸 Oakland, California, United States

Valley Medical Oncology Consultants; 🇺🇸 Pleasanton, California, United States

Stanford Cancer Institute Palo Alto; 🇺🇸 Palo Alto, California, United States

Kaiser Permanente-Redwood City; 🇺🇸 Redwood City, California, United States

Rohnert Park Cancer Center; 🇺🇸 Rohnert Park, California, United States

Sutter Cancer Centers Radiation Oncology Services-Roseville; 🇺🇸 Roseville, California, United States

Kaiser Permanente-Rancho Cordova Cancer Center; 🇺🇸 Rancho Cordova, California, United States

Kaiser Permanente-Roseville; 🇺🇸 Roseville, California, United States

Kaiser Permanente-Santa Teresa-San Jose; 🇺🇸 San Jose, California, United States

Kaiser Permanente San Leandro; 🇺🇸 San Leandro, California, United States

Kaiser Permanente-San Rafael; 🇺🇸 San Rafael, California, United States

Kaiser Permanente-Santa Rosa; 🇺🇸 Santa Rosa, California, United States

Kaiser Permanente Cancer Treatment Center; 🇺🇸 South San Francisco, California, United States

Kaiser Permanente-Stockton; 🇺🇸 Stockton, California, United States

Kaiser Permanente-South San Francisco; 🇺🇸 South San Francisco, California, United States

Sutter Cancer Centers Radiation Oncology Services-Vacaville; 🇺🇸 Vacaville, California, United States

Kaiser Permanente Medical Center-Vacaville; 🇺🇸 Vacaville, California, United States

Kaiser Permanente-Walnut Creek; 🇺🇸 Walnut Creek, California, United States

Rocky Mountain Cancer Centers-Aurora; 🇺🇸 Aurora, Colorado, United States

Boulder Community Hospital; 🇺🇸 Boulder, Colorado, United States

Rocky Mountain Cancer Centers-Boulder; 🇺🇸 Boulder, Colorado, United States

Rocky Mountain Cancer Centers-Penrose; 🇺🇸 Colorado Springs, Colorado, United States

Penrose-Saint Francis Healthcare; 🇺🇸 Colorado Springs, Colorado, United States

Colorado Blood Cancer Institute; 🇺🇸 Denver, Colorado, United States

Mercy Medical Center; 🇺🇸 Durango, Colorado, United States

Mountain Blue Cancer Care Center; 🇺🇸 Golden, Colorado, United States

Swedish Medical Center; 🇺🇸 Englewood, Colorado, United States

Rocky Mountain Cancer Centers-Greenwood Village; 🇺🇸 Greenwood Village, Colorado, United States

North Colorado Medical Center; 🇺🇸 Greeley, Colorado, United States

McKee Medical Center; 🇺🇸 Loveland, Colorado, United States

Middlesex Hospital; 🇺🇸 Middletown, Connecticut, United States

Christiana Gynecologic Oncology LLC; 🇺🇸 Newark, Delaware, United States

Beebe Health Campus; 🇺🇸 Rehoboth Beach, Delaware, United States

Medical Oncology Hematology Consultants PA; 🇺🇸 Newark, Delaware, United States

Kootenai Health - Coeur d'Alene; 🇺🇸 Coeur d'Alene, Idaho, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler; 🇺🇸 Savannah, Georgia, United States

Cancer Care Specialists of Illinois - Decatur; 🇺🇸 Decatur, Illinois, United States

Decatur Memorial Hospital; 🇺🇸 Decatur, Illinois, United States

Loyola University Medical Center; 🇺🇸 Maywood, Illinois, United States

Trinity Medical Center; 🇺🇸 Moline, Illinois, United States

Franciscan Saint Francis Health-Beech Grove; 🇺🇸 Beech Grove, Indiana, United States

Michiana Hematology Oncology PC-Mishawaka; 🇺🇸 Mishawaka, Indiana, United States

West Suburban Medical Center; 🇺🇸 River Forest, Illinois, United States

SwedishAmerican Regional Cancer Center/ACT; 🇺🇸 Rockford, Illinois, United States

Elkhart Clinic; 🇺🇸 Elkhart, Indiana, United States

Elkhart General Hospital; 🇺🇸 Elkhart, Indiana, United States

Michiana Hematology Oncology PC-Elkhart; 🇺🇸 Elkhart, Indiana, United States

Saint Joseph Regional Medical Center-Mishawaka; 🇺🇸 Mishawaka, Indiana, United States

Constantinou, Costas L MD (UIA Investigator); 🇺🇸 Bettendorf, Iowa, United States

Northern Indiana Cancer Research Consortium; 🇺🇸 South Bend, Indiana, United States

Siouxland Regional Cancer Center; 🇺🇸 Sioux City, Iowa, United States

McFarland Clinic - Marshalltown; 🇺🇸 Marshalltown, Iowa, United States

Mercy Medical Center-Sioux City; 🇺🇸 Sioux City, Iowa, United States

Salina Regional Health Center; 🇺🇸 Salina, Kansas, United States

Oncology Hematology Care Inc-Crestview; 🇺🇸 Crestview Hills, Kentucky, United States

Central Maine Medical Center; 🇺🇸 Lewiston, Maine, United States

Maine Medical Center- Scarborough Campus; 🇺🇸 Scarborough, Maine, United States

Greater Baltimore Medical Center; 🇺🇸 Baltimore, Maryland, United States

Maine Medical Center-Bramhall Campus; 🇺🇸 Portland, Maine, United States

UM Upper Chesapeake Medical Center; 🇺🇸 Bel Air, Maryland, United States

Brigham and Women's Hospital; 🇺🇸 Boston, Massachusetts, United States

Dana-Farber Cancer Institute; 🇺🇸 Boston, Massachusetts, United States

Lahey Hospital and Medical Center; 🇺🇸 Burlington, Massachusetts, United States

Baystate Medical Center; 🇺🇸 Springfield, Massachusetts, United States

Dana-Farber/Brigham and Women's Cancer Center at South Shore; 🇺🇸 South Weymouth, Massachusetts, United States

D'Amour Center for Cancer Care; 🇺🇸 Springfield, Massachusetts, United States

Berkshire Medical Center - Cancer Center; 🇺🇸 Pittsfield, Massachusetts, United States

Henry Ford Macomb Hospital-Clinton Township; 🇺🇸 Clinton Township, Michigan, United States

Beaumont Hospital - Dearborn; 🇺🇸 Dearborn, Michigan, United States

Henry Ford Cancer Institute-Downriver; 🇺🇸 Brownstown, Michigan, United States

Borgess Medical Center; 🇺🇸 Kalamazoo, Michigan, United States

Genesys Hurley Cancer Institute; 🇺🇸 Flint, Michigan, United States

West Michigan Cancer Center; 🇺🇸 Kalamazoo, Michigan, United States

Sparrow Hospital; 🇺🇸 Lansing, Michigan, United States

Bronson Methodist Hospital; 🇺🇸 Kalamazoo, Michigan, United States

Toledo Clinic Cancer Centers-Monroe; 🇺🇸 Monroe, Michigan, United States

Lake Huron Medical Center; 🇺🇸 Port Huron, Michigan, United States

Saint Joseph Mercy Oakland; 🇺🇸 Pontiac, Michigan, United States

Marie Yeager Cancer Center; 🇺🇸 Saint Joseph, Michigan, United States

Ascension Saint Mary's Hospital; 🇺🇸 Rhinelander, Wisconsin, United States

Lakeland Medical Center Saint Joseph; 🇺🇸 Saint Joseph, Michigan, United States

Ascension Providence Hospitals - Southfield; 🇺🇸 Southfield, Michigan, United States

Fairview Ridges Hospital; 🇺🇸 Burnsville, Minnesota, United States

Unity Hospital; 🇺🇸 Fridley, Minnesota, United States

Coborn Cancer Center at Saint Cloud Hospital; 🇺🇸 Saint Cloud, Minnesota, United States

Parkland Health Center-Bonne Terre; 🇺🇸 Bonne Terre, Missouri, United States

Cox Cancer Center Branson; 🇺🇸 Branson, Missouri, United States

Siteman Cancer Center at West County Hospital; 🇺🇸 Creve Coeur, Missouri, United States

Centerpoint Medical Center LLC; 🇺🇸 Independence, Missouri, United States

Mercy Hospital Joplin; 🇺🇸 Joplin, Missouri, United States

Mercy Hospital Saint Louis; 🇺🇸 Saint Louis, Missouri, United States

Siteman Cancer Center at Saint Peters Hospital; 🇺🇸 Saint Peters, Missouri, United States

Mercy Hospital South; 🇺🇸 Saint Louis, Missouri, United States

Sainte Genevieve County Memorial Hospital; 🇺🇸 Sainte Genevieve, Missouri, United States

Saint Louis-Cape Girardeau CCOP; 🇺🇸 Saint Louis, Missouri, United States

Saint Patrick Hospital - Community Hospital; 🇺🇸 Missoula, Montana, United States

Cancer and Blood Specialists-Henderson; 🇺🇸 Henderson, Nevada, United States

Summerlin Hospital Medical Center; 🇺🇸 Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central Valley; 🇺🇸 Las Vegas, Nevada, United States

Concord Hospital; 🇺🇸 Concord, New Hampshire, United States

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center; 🇺🇸 Lebanon, New Hampshire, United States

Wentworth-Douglass Hospital; 🇺🇸 Dover, New Hampshire, United States

Memorial Sloan Kettering Basking Ridge; 🇺🇸 Basking Ridge, New Jersey, United States

Virtua Memorial; 🇺🇸 Mount Holly, New Jersey, United States

Newark Beth Israel Medical Center; 🇺🇸 Newark, New Jersey, United States

Sparta Cancer Treatment Center; 🇺🇸 Sparta, New Jersey, United States

Capital Health Medical Center-Hopewell; 🇺🇸 Pennington, New Jersey, United States

Overlook Hospital; 🇺🇸 Summit, New Jersey, United States

Delaware Radiation Oncology; 🇺🇸 Delaware, Ohio, United States

Grady Memorial Hospital; 🇺🇸 Delaware, Ohio, United States

Memorial Sloan Kettering Westchester; 🇺🇸 Harrison, New York, United States

University Hospitals Parma Medical Center; 🇺🇸 Parma, Ohio, United States

Sands Cancer Center; 🇺🇸 Canandaigua, New York, United States

Southern Ohio Medical Center; 🇺🇸 Portsmouth, Ohio, United States

Mount Sinai Union Square; 🇺🇸 New York, New York, United States

Memorial Sloan Kettering Cancer Center; 🇺🇸 New York, New York, United States

Memorial Sloan Kettering Sleepy Hollow; 🇺🇸 Sleepy Hollow, New York, United States

Memorial Sloan Kettering Nassau; 🇺🇸 Uniondale, New York, United States

Novant Health Presbyterian Medical Center; 🇺🇸 Charlotte, North Carolina, United States

Vidant Oncology-Kinston; 🇺🇸 Kinston, North Carolina, United States

Atrium Health Union/LCI-Union; 🇺🇸 Monroe, North Carolina, United States

Strecker Cancer Center-Belpre; 🇺🇸 Belpre, Ohio, United States

Oncology Hematology Care Inc-Eden Park; 🇺🇸 Cincinnati, Ohio, United States

University of Cincinnati Cancer Center-UC Medical Center; 🇺🇸 Cincinnati, Ohio, United States

Adena Regional Medical Center; 🇺🇸 Chillicothe, Ohio, United States

Oncology Hematology Care Inc-Anderson; 🇺🇸 Cincinnati, Ohio, United States

Columbus Oncology and Hematology Associates Inc; 🇺🇸 Columbus, Ohio, United States

Ohio State University Comprehensive Cancer Center; 🇺🇸 Columbus, Ohio, United States

Riverside Methodist Hospital; 🇺🇸 Columbus, Ohio, United States

Columbus NCI Community Oncology Research Program; 🇺🇸 Columbus, Ohio, United States

Grant Medical Center; 🇺🇸 Columbus, Ohio, United States

The Mark H Zangmeister Center; 🇺🇸 Columbus, Ohio, United States

Mount Carmel Health Center West; 🇺🇸 Columbus, Ohio, United States

Doctors Hospital; 🇺🇸 Columbus, Ohio, United States

Good Samaritan Hospital - Dayton; 🇺🇸 Dayton, Ohio, United States

Miami Valley Hospital; 🇺🇸 Dayton, Ohio, United States

Miami Valley Hospital North; 🇺🇸 Dayton, Ohio, United States

Delaware Health Center-Grady Cancer Center; 🇺🇸 Delaware, Ohio, United States

Oncology Hematology Care Inc-Healthplex; 🇺🇸 Fairfield, Ohio, United States

Wayne Hospital; 🇺🇸 Greenville, Ohio, United States

Kettering Medical Center; 🇺🇸 Kettering, Ohio, United States

UH Seidman Cancer Center at Lake Health Mentor Campus; 🇺🇸 Mentor, Ohio, United States

Summa Health Medina Medical Center; 🇺🇸 Medina, Ohio, United States

Lancaster Radiation Oncology; 🇺🇸 Lancaster, Ohio, United States

Toledo Radiation Oncology at Northwest Ohio Onocolgy Center; 🇺🇸 Maumee, Ohio, United States

Toledo Clinic Cancer Centers-Maumee; 🇺🇸 Maumee, Ohio, United States

Marietta Memorial Hospital; 🇺🇸 Marietta, Ohio, United States

UH Seidman Cancer Center at Southwest General Hospital; 🇺🇸 Middleburg Heights, Ohio, United States

Springfield Regional Medical Center; 🇺🇸 Springfield, Ohio, United States

Saint Charles Hospital; 🇺🇸 Oregon, Ohio, United States

Newark Radiation Oncology; 🇺🇸 Newark, Ohio, United States

Licking Memorial Hospital; 🇺🇸 Newark, Ohio, United States

Toledo Clinic Cancer Centers-Oregon; 🇺🇸 Oregon, Ohio, United States

North Coast Cancer Care; 🇺🇸 Sandusky, Ohio, United States

University Hospitals Portage Medical Center; 🇺🇸 Ravenna, Ohio, United States

UH Seidman Cancer Center at Salem Regional Medical Center; 🇺🇸 Salem, Ohio, United States

UH Seidman Cancer Center at Firelands Regional Medical Center; 🇺🇸 Sandusky, Ohio, United States

University of Toledo; 🇺🇸 Toledo, Ohio, United States

Toledo Community Hospital Oncology Program CCOP; 🇺🇸 Toledo, Ohio, United States

Mercy Health - Saint Anne Hospital; 🇺🇸 Toledo, Ohio, United States

Upper Valley Medical Center; 🇺🇸 Troy, Ohio, United States

Saint Ann's Hospital; 🇺🇸 Westerville, Ohio, United States

University of Cincinnati Cancer Center-West Chester; 🇺🇸 West Chester, Ohio, United States

Cancer Treatment Center; 🇺🇸 Wooster, Ohio, United States

Oklahoma Cancer Specialists and Research Institute-Tulsa; 🇺🇸 Tulsa, Oklahoma, United States

Providence Milwaukie Hospital; 🇺🇸 Milwaukie, Oregon, United States

UHHS-Westlake Medical Center; 🇺🇸 Westlake, Ohio, United States

Clackamas Radiation Oncology Center; 🇺🇸 Clackamas, Oregon, United States

Genesis Healthcare System Cancer Care Center; 🇺🇸 Zanesville, Ohio, United States

Providence Newberg Medical Center; 🇺🇸 Newberg, Oregon, United States

Providence Willamette Falls Medical Center; 🇺🇸 Oregon City, Oregon, United States

Providence Saint Vincent Medical Center; 🇺🇸 Portland, Oregon, United States

UPMC-Heritage Valley Health System Beaver; 🇺🇸 Beaver, Pennsylvania, United States

Salem Hospital; 🇺🇸 Salem, Oregon, United States

Geisinger Medical Center; 🇺🇸 Danville, Pennsylvania, United States

Bryn Mawr Hospital; 🇺🇸 Bryn Mawr, Pennsylvania, United States

Northeast Radiation Oncology Center; 🇺🇸 Dunmore, Pennsylvania, United States

UPMC Cancer Centers - Arnold Palmer Pavilion; 🇺🇸 Greensburg, Pennsylvania, United States

UPMC-Johnstown/John P. Murtha Regional Cancer Center; 🇺🇸 Johnstown, Pennsylvania, United States

UPMC Cancer Center at UPMC McKeesport; 🇺🇸 McKeesport, Pennsylvania, United States

UPMC Hillman Cancer Center in Coraopolis; 🇺🇸 Moon, Pennsylvania, United States

Allegheny Valley Hospital; 🇺🇸 Natrona Heights, Pennsylvania, United States

UPMC Cancer Center-Natrona Heights; 🇺🇸 Natrona Heights, Pennsylvania, United States

Paoli Memorial Hospital; 🇺🇸 Paoli, Pennsylvania, United States

American College of Radiology Imaging Network; 🇺🇸 Philadelphia, Pennsylvania, United States

UPMC-Saint Margaret; 🇺🇸 Pittsburgh, Pennsylvania, United States

UPMC-Shadyside Hospital; 🇺🇸 Pittsburgh, Pennsylvania, United States

UPMC Jefferson Regional Radiation Oncology; 🇺🇸 Pittsburgh, Pennsylvania, United States

UPMC-Passavant Hospital; 🇺🇸 Pittsburgh, Pennsylvania, United States

UPMC-Saint Clair Hospital Cancer Center; 🇺🇸 Pittsburgh, Pennsylvania, United States

UPMC Uniontown Hospital Radiation Oncology; 🇺🇸 Uniontown, Pennsylvania, United States

UPMC Cancer Center at UPMC Northwest; 🇺🇸 Seneca, Pennsylvania, United States

UPMC Washington Hospital Radiation Oncology; 🇺🇸 Washington, Pennsylvania, United States

Reading Hospital; 🇺🇸 West Reading, Pennsylvania, United States

Wexford Health and Wellness Pavilion; 🇺🇸 Wexford, Pennsylvania, United States

Lankenau Medical Center; 🇺🇸 Wynnewood, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center; 🇺🇸 Wilkes-Barre, Pennsylvania, United States

Main Line Health NCORP; 🇺🇸 Wynnewood, Pennsylvania, United States

Miriam Hospital; 🇺🇸 Providence, Rhode Island, United States

AnMed Health Cancer Center; 🇺🇸 Anderson, South Carolina, United States

Prisma Health Cancer Institute - Easley; 🇺🇸 Easley, South Carolina, United States

Prisma Health Cancer Institute - Butternut; 🇺🇸 Greenville, South Carolina, United States

Prisma Health Cancer Institute - Faris; 🇺🇸 Greenville, South Carolina, United States

Prisma Health Greenville Memorial Hospital; 🇺🇸 Greenville, South Carolina, United States

Prisma Health Cancer Institute - Eastside; 🇺🇸 Greenville, South Carolina, United States

Prisma Health Cancer Institute - Seneca; 🇺🇸 Seneca, South Carolina, United States

Rock Hill Radiation Therapy Center; 🇺🇸 Rock Hill, South Carolina, United States

Ballad Health Cancer Care - Kingsport; 🇺🇸 Kingsport, Tennessee, United States

Spartanburg Medical Center; 🇺🇸 Spartanburg, South Carolina, United States

UT Southwestern/Simmons Cancer Center-Dallas; 🇺🇸 Dallas, Texas, United States

University of Texas Medical Branch; 🇺🇸 Galveston, Texas, United States

Houston Methodist Hospital; 🇺🇸 Houston, Texas, United States

Vanderbilt University/Ingram Cancer Center; 🇺🇸 Nashville, Tennessee, United States

UTMB Cancer Center at Victory Lakes; 🇺🇸 League City, Texas, United States

Covenant Medical Center-Lakeside; 🇺🇸 Lubbock, Texas, United States

Sandra L Maxwell Cancer Center; 🇺🇸 Cedar City, Utah, United States

Logan Regional Hospital; 🇺🇸 Logan, Utah, United States

McKay-Dee Hospital Center; 🇺🇸 Ogden, Utah, United States

Utah Valley Regional Medical Center; 🇺🇸 Provo, Utah, United States

Intermountain Medical Center; 🇺🇸 Murray, Utah, United States

Norris Cotton Cancer Center-North; 🇺🇸 Saint Johnsbury, Vermont, United States

Cancer Care Center at Island Hospital; 🇺🇸 Anacortes, Washington, United States

Fredericksburg Oncology Inc; 🇺🇸 Fredericksburg, Virginia, United States

Danville Regional Medical Center; 🇺🇸 Danville, Virginia, United States

Southwest VA Regional Cancer Center; 🇺🇸 Norton, Virginia, United States

MultiCare Auburn Medical Center; 🇺🇸 Auburn, Washington, United States

Overlake Medical Center; 🇺🇸 Bellevue, Washington, United States

PeaceHealth Saint Joseph Medical Center; 🇺🇸 Bellingham, Washington, United States

Harrison HealthPartners Hematology and Oncology-Bremerton; 🇺🇸 Bremerton, Washington, United States

Harrison Medical Center; 🇺🇸 Bremerton, Washington, United States

Highline Medical Center-Main Campus; 🇺🇸 Burien, Washington, United States

Kadlec Clinic Hematology and Oncology; 🇺🇸 Kennewick, Washington, United States

Providence Regional Cancer Partnership; 🇺🇸 Everett, Washington, United States

Swedish Cancer Institute-Issaquah; 🇺🇸 Issaquah, Washington, United States

Saint Francis Hospital; 🇺🇸 Federal Way, Washington, United States

Providence Regional Cancer System-Lacey; 🇺🇸 Lacey, Washington, United States

Skagit Valley Hospital; 🇺🇸 Mount Vernon, Washington, United States

Saint Clare Hospital; 🇺🇸 Lakewood, Washington, United States

PeaceHealth Saint John Medical Center; 🇺🇸 Longview, Washington, United States

Providence - Saint Peter Hospital; 🇺🇸 Olympia, Washington, United States

Capital Medical Center; 🇺🇸 Olympia, Washington, United States

Harrison HealthPartners Hematology and Oncology-Poulsbo; 🇺🇸 Poulsbo, Washington, United States

Fred Hutchinson Cancer Research Center; 🇺🇸 Seattle, Washington, United States

Kaiser Permanente Washington; 🇺🇸 Seattle, Washington, United States

Olympic Medical Cancer Care Center; 🇺🇸 Sequim, Washington, United States

Cancer Care Northwest - Spokane South; 🇺🇸 Spokane, Washington, United States

MultiCare Tacoma General Hospital; 🇺🇸 Tacoma, Washington, United States

Northwest Medical Specialties PLLC; 🇺🇸 Tacoma, Washington, United States

Evergreen Hematology and Oncology PS; 🇺🇸 Spokane, Washington, United States

MultiCare Allenmore Hospital; 🇺🇸 Tacoma, Washington, United States

Northwest NCI Community Oncology Research Program; 🇺🇸 Tacoma, Washington, United States

Saint Joseph Medical Center; 🇺🇸 Tacoma, Washington, United States

Wenatchee Valley Hospital and Clinics; 🇺🇸 Wenatchee, Washington, United States

West Virginia University Charleston Division; 🇺🇸 Charleston, West Virginia, United States

Wheeling Hospital/Schiffler Cancer Center; 🇺🇸 Wheeling, West Virginia, United States

Aurora Cancer Care-Southern Lakes VLCC; 🇺🇸 Burlington, Wisconsin, United States

HSHS Sacred Heart Hospital; 🇺🇸 Eau Claire, Wisconsin, United States

Aurora Health Care Germantown Health Center; 🇺🇸 Germantown, Wisconsin, United States

Marshfield Clinic Cancer Center at Sacred Heart; 🇺🇸 Eau Claire, Wisconsin, United States

Green Bay Oncology at Saint Vincent Hospital; 🇺🇸 Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center Green Bay; 🇺🇸 Green Bay, Wisconsin, United States

Green Bay Oncology Limited at Saint Mary's Hospital; 🇺🇸 Green Bay, Wisconsin, United States

Aurora BayCare Medical Center; 🇺🇸 Green Bay, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Saint Mary's; 🇺🇸 Green Bay, Wisconsin, United States

Gundersen Lutheran Medical Center; 🇺🇸 La Crosse, Wisconsin, United States

Aurora Cancer Care-Kenosha South; 🇺🇸 Kenosha, Wisconsin, United States

Aurora Bay Area Medical Group-Marinette; 🇺🇸 Marinette, Wisconsin, United States

Bay Area Medical Center; 🇺🇸 Marinette, Wisconsin, United States

Aurora Cancer Care-Milwaukee; 🇺🇸 Milwaukee, Wisconsin, United States

Marshfield Medical Center-Marshfield; 🇺🇸 Marshfield, Wisconsin, United States

Marshfield Medical Center; 🇺🇸 Marshfield, Wisconsin, United States

Zablocki Veterans Administration Medical Center; 🇺🇸 Milwaukee, Wisconsin, United States

Marshfield Clinic-Minocqua Center; 🇺🇸 Minocqua, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Oconto Falls; 🇺🇸 Oconto Falls, Wisconsin, United States

Cancer Center of Western Wisconsin; 🇺🇸 New Richmond, Wisconsin, United States

Vince Lombardi Cancer Clinic - Oshkosh; 🇺🇸 Oshkosh, Wisconsin, United States

Ascension Saint Michael's Hospital; 🇺🇸 Stevens Point, Wisconsin, United States

Aurora Cancer Care-Racine; 🇺🇸 Racine, Wisconsin, United States

Saint Vincent Hospital Cancer Center at Sturgeon Bay; 🇺🇸 Sturgeon Bay, Wisconsin, United States

Marshfield Medical Center-Rice Lake; 🇺🇸 Rice Lake, Wisconsin, United States

Vince Lombardi Cancer Clinic-Sheboygan; 🇺🇸 Sheboygan, Wisconsin, United States

Aurora Medical Center in Summit; 🇺🇸 Summit, Wisconsin, United States

Green Bay Oncology - Sturgeon Bay; 🇺🇸 Sturgeon Bay, Wisconsin, United States

Aurora Cancer Care-Milwaukee West; 🇺🇸 Wauwatosa, Wisconsin, United States

Vince Lombardi Cancer Clinic-Two Rivers; 🇺🇸 Two Rivers, Wisconsin, United States

Aurora Cancer Care-Waukesha; 🇺🇸 Waukesha, Wisconsin, United States

Aurora West Allis Medical Center; 🇺🇸 West Allis, Wisconsin, United States

Froedtert West Bend Hospital/Kraemer Cancer Center; 🇺🇸 West Bend, Wisconsin, United States

Diagnostic and Treatment Center; 🇺🇸 Weston, Wisconsin, United States

Hurley Medical Center; 🇺🇸 Flint, Michigan, United States

Sutter Cancer Centers Radiation Oncology Services-Cameron Park; 🇺🇸 Cameron Park, California, United States

Jefferson Torresdale Hospital; 🇺🇸 Philadelphia, Pennsylvania, United States

Prisma Health Cancer Institute - Greer; 🇺🇸 Greer, South Carolina, United States

Fulton County Health Center; 🇺🇸 Wauseon, Ohio, United States

Thomas Jefferson University Hospital; 🇺🇸 Philadelphia, Pennsylvania, United States

Fox Chase Cancer Center; 🇺🇸 Philadelphia, Pennsylvania, United States

Allegheny General Hospital; 🇺🇸 Pittsburgh, Pennsylvania, United States

American Fork Hospital / Huntsman Intermountain Cancer Center; 🇺🇸 American Fork, Utah, United States

Providence Regional Cancer System-Centralia; 🇺🇸 Centralia, Washington, United States

PeaceHealth Southwest Medical Center; 🇺🇸 Vancouver, Washington, United States

Compass Oncology Vancouver; 🇺🇸 Vancouver, Washington, United States

Sutter Medical Center Sacramento; 🇺🇸 Sacramento, California, United States

University of California Davis Comprehensive Cancer Center; 🇺🇸 Sacramento, California, United States

Kaiser Permanente-South Sacramento; 🇺🇸 Sacramento, California, United States

South Sacramento Cancer Center; 🇺🇸 Sacramento, California, United States

Kaiser Permanente - Sacramento; 🇺🇸 Sacramento, California, United States

Michigan Cancer Research Consortium NCORP; 🇺🇸 Ann Arbor, Michigan, United States

Saint Joseph Mercy Hospital; 🇺🇸 Ann Arbor, Michigan, United States

University of Michigan Comprehensive Cancer Center; 🇺🇸 Ann Arbor, Michigan, United States

Wake Forest University Health Sciences; 🇺🇸 Winston-Salem, North Carolina, United States

AdventHealth East Orlando; 🇺🇸 Orlando, Florida, United States

AdventHealth Orlando; 🇺🇸 Orlando, Florida, United States

South Bend Clinic; 🇺🇸 South Bend, Indiana, United States

Michiana Hematology Oncology PC-South Bend; 🇺🇸 South Bend, Indiana, United States

Medical Center of Central Georgia; 🇺🇸 Macon, Georgia, United States

Kootenai Clinic Cancer Services - Post Falls; 🇺🇸 Post Falls, Idaho, United States

Yale University; 🇺🇸 New Haven, Connecticut, United States

Saint Luke's Hospital of Kansas City; 🇺🇸 Kansas City, Missouri, United States

North Kansas City Hospital; 🇺🇸 Kansas City, Missouri, United States

Heartland Hematology and Oncology Associates Incorporated; 🇺🇸 Kansas City, Missouri, United States

The University of Kansas Cancer Center-South; 🇺🇸 Kansas City, Missouri, United States

Research Medical Center; 🇺🇸 Kansas City, Missouri, United States

University of Kansas Cancer Center - North; 🇺🇸 Kansas City, Missouri, United States

Medical University of South Carolina; 🇺🇸 Charleston, South Carolina, United States

Saint Vincent Healthcare; 🇺🇸 Billings, Montana, United States

Saint James Community Hospital and Cancer Treatment Center; 🇺🇸 Butte, Montana, United States

Bozeman Deaconess Hospital; 🇺🇸 Bozeman, Montana, United States

Saint Peter's Community Hospital; 🇺🇸 Helena, Montana, United States

Mercy Medical Center - Des Moines; 🇺🇸 Des Moines, Iowa, United States

Baptist Health Lexington; 🇺🇸 Lexington, Kentucky, United States

Iowa-Wide Oncology Research Coalition NCORP; 🇺🇸 Des Moines, Iowa, United States

Iowa Methodist Medical Center; 🇺🇸 Des Moines, Iowa, United States

Ochsner Medical Center Jefferson; 🇺🇸 New Orleans, Louisiana, United States

University of Kentucky/Markey Cancer Center; 🇺🇸 Lexington, Kentucky, United States

University of New Mexico Cancer Center; 🇺🇸 Albuquerque, New Mexico, United States

Montefiore Medical Center-Weiler Hospital; 🇺🇸 Bronx, New York, United States

Montefiore Medical Center - Moses Campus; 🇺🇸 Bronx, New York, United States

Wilmot Cancer Institute Radiation Oncology at Greece; 🇺🇸 Rochester, New York, United States

Highland Hospital; 🇺🇸 Rochester, New York, United States

University of Rochester; 🇺🇸 Rochester, New York, United States

Banner University Medical Center - Tucson; 🇺🇸 Tucson, Arizona, United States

Southeast Cancer Center; 🇺🇸 Cape Girardeau, Missouri, United States

Rhode Island Hospital; 🇺🇸 Providence, Rhode Island, United States