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Clinical Trials/NCT03980067
NCT03980067
Completed
Not Applicable

Pediatric Procedural Sedation and the Relationship With Post-Discharge Negative Behavioral Changes in the Emergency Department

Medical College of Wisconsin1 site in 1 country201 target enrollmentMay 17, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Behavior, Child
Sponsor
Medical College of Wisconsin
Enrollment
201
Locations
1
Primary Endpoint
Post-Hospitalization Behavior Questionnaire (PHBQ)
Status
Completed
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to evaluate if a virtual reality (VR) distraction game played prior to procedural sedation for long bone fracture reduction will improve post-discharge negative behavior changes following discharge from the pediatric Emergency Department (ED).

Detailed Description

This randomized control trial will investigate the use of a virtual reality (VR) distraction game prior to IV ketamine procedural sedation for long bone fracture reduction. Prior studies have demonstrated that children undergoing anesthesia or procedural sedation can have lingering negative behavioral changes lasting several weeks after discharge home. Children who are anxious have higher rates of developing negative behavior changes. Opiate pain control and pre-operative instructional workshops have demonstrated efficacy in decreasing negative behavior outcomes. There is some evidence that distraction techniques, such as VR, can alleviate pre-procedural anxiety and pain during procedures. To our knowledge, evaluating the use of a non-pharmacologic, virtual reality intervention and its effects on reducing post-discharge negative behavior changes following discharge from the Emergency Department has not been evaluated.

Registry
clinicaltrials.gov
Start Date
May 17, 2019
End Date
May 12, 2022
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Amy Drendel

Professor, DO, MS

Medical College of Wisconsin

Eligibility Criteria

Inclusion Criteria

  • Children ages 6 years to 17.5 years old receiving procedural sedation with IV ketamine in the Children's Hospital of Wisconsin Emergency Department for long bone fracture reduction

Exclusion Criteria

  • Moderate to severe developmental delay
  • Non-English-speaking participants or parent/guardian
  • Taking psychotropic medications
  • History of severe motion sickness
  • Currently experiencing nausea/vomiting
  • History of severe visual impairment
  • History of seizures
  • Expected admission to the hospital post-procedure

Outcomes

Primary Outcomes

Post-Hospitalization Behavior Questionnaire (PHBQ)

Time Frame: 24 months

Post-Hospitalization Behavior Questionnaire, a parent-report tool, with 27 items in six categories, comprising general, separation, and sleep anxieties, eating disturbance, aggression towards authority, apathy/withdrawal accesses negative behavioral changes in children post-surgery, hospitalization (Kain et al., 1996, Kain et al., 1999) or after minor ED procedures (Brodzinski et al., 2013). It takes 10 minutes and is given prior to the sedation and at 1-week via text/email, phone, or mail follow up post-discharge. Parents compare their child's behavior pre-hospitalization to post using the following: much less than before (1), less than before (2), same as before (3), more than before (4), and much more than before (5). Scores above 3 indicate greater maladaptive behavioral changes, below 3 indicate improvements and 3 indicates no change in behavior.

Secondary Outcomes

  • Modified Yale Preoperative Anxiety Scale (m-YPAS)(24 months)

Study Sites (1)

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