Efficacy and safety of acclerated repetitive transcranial magnetic stimulation for patients with major depressive disorder

Not Applicable

Recruiting

• Conditions: Mental and behavioral disorders

• Registration Number: KCT0000666
• Lead Sponsor: Yonsei University Health System, Gangnam Severance Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 March 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients taking two or less antidepressant medications without change of dosage within two weeks
- Illness duation is less than 5 years
- Montgomery-Asberg Depression Rating Scale score is equal to or higher than 22

Exclusion Criteria

- Patient who has other Axis I disoder including schizophrenia, bipolar disorder and so on.
- Patient who has been treated with rTMS or electroconvulsive therapy.
- Past history of seizure disorder
- 1st degree family history of seizure disorder
- Substance dependence or other medical illnesses which have significant effect on brain function
- Organic brain disease such as brain tumor or intracranial hemorrhage
- Patients who have taken medication lowering seizure threshold (ex: theophylline)
- Patients who have artificial metal in the body (cochlear implantation or pacemaker)
- Clinically inappropriate patient for rTMS

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hamilton Depression Rating Scale

Secondary Outcome Measures

Name	Time	Method
Frequency, Intensity, Burden of Side Effect Rating scale