Olfactory and Visual Perception in Depressed Patients

Not Applicable

Terminated

• Conditions: Depression
• Interventions: Behavioral: olfactory assessment; Behavioral: image visualization; Behavioral: psychophysiological assessment

• Registration Number: NCT02857088
• Lead Sponsor: Centre Hospitalier Universitaire de Besancon

Brief Summary

The study aimed to determine the emotional reactivity of depressed patients to visual and olfactory stimuli in comparison with healthy volunteers.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-02
• Primary Completion: 2014-04
• Study Completion: 2016-04
• Study First Submitted: 2016-07-26
• Status Verified: 2016-08
• Study First Submitted QC: 2016-08-02
• Last Update Submitted: 2016-08-02
• Study First Posted: 2016-08-05
• Last Update Posted: 2016-08-05

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 3

Inclusion Criteria

• no cognitive impairment that could prevent instruction comprehension
• no more than 10 cigarettes/day
• signed informed consent
• group 1: current major depressive disorder
• group 2: no current major depressive disorder

Exclusion Criteria

• pregnancy
• visual impairment
• olfactory impairment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
depressed patients	psychophysiological assessment	patient with a current unipolar major depressive disorder intervention: olfactory assessment, image visualization and psychophysiological assessment
non depressed subject	image visualization	subject without a current unipolar major depressive disorder intervention: olfactory assessment, image visualization and psychophysiological assessment
depressed patients	olfactory assessment	patient with a current unipolar major depressive disorder intervention: olfactory assessment, image visualization and psychophysiological assessment
depressed patients	image visualization	patient with a current unipolar major depressive disorder intervention: olfactory assessment, image visualization and psychophysiological assessment
non depressed subject	olfactory assessment	subject without a current unipolar major depressive disorder intervention: olfactory assessment, image visualization and psychophysiological assessment
non depressed subject	psychophysiological assessment	subject without a current unipolar major depressive disorder intervention: olfactory assessment, image visualization and psychophysiological assessment

Primary Outcome Measures

Name	Time	Method
hedonicity score of visual stimuli	up to 1 month	it will be compared between depressed and non depressed subjects.
skin conductance reactivity amplitude	up to 1 month	it will be compared between depressed and non depressed subjects.
Skin conductance reactivity reaction time	up to 1 month	it will be compared between depressed and non depressed subjects.
hedonicity score of olfactory stimuli	up to 1 month	it will be compared between depressed and non depressed subjects.

Trial Locations

Locations (1)

CHU Besancon; 🇫🇷 Besancon, Doubs, France