MedPath

Decipher Genomics Resource for Intelligent Discovery

Conditions
Bladder Cancer
Renal Cancer
Prostate Cancer
Interventions
Other: Decipher Cancer Classifier
Registration Number
NCT02609269
Lead Sponsor
GenomeDx Biosciences Corp
Brief Summary

To prospectively evaluate the utility of genomic expression data as a tool to better characterize the tumors of individual patients, and to understand how genomic information from individual patients undergoing routine clinical testing can be used in population-level analysis to improve treatment and outcomes.

Detailed Description

Observational study involving the release of tumor genome-wide expression data generated by the Decipher assay which will be linked to clinical treatment and outcome data for patients in whom Decipher clinical testing was performed. The GRID database population will be used to characterize the genomics of cancer and discover or validate gene expression signatures that may be useful for understanding of the biology of the disease and implementing precision medicine approaches for cancer patients.

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
1000000
Inclusion Criteria

Subjects that have had a Decipher clinical test

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Decipher GRID PatientsDecipher Cancer ClassifierPatients who have been tested with any of the Decipher clinical tests
Primary Outcome Measures
NameTimeMethod
Link complete genomic RNA expression array data generated from Decipher testing with clinical data for patients who consent to participate.Through study completion, an average of 1 year

Role of genomic expression data in the biology of certain cancers

Secondary Outcome Measures
NameTimeMethod
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