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Clinical Trials/NCT04478045
NCT04478045
Completed
Not Applicable

The Application of Point-of-care Ultrasonography in Differential Diagnosis of Shock in Emergency and Critical Care

National Taiwan University Hospital1 site in 1 country278 target enrollmentAugust 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Shock
Sponsor
National Taiwan University Hospital
Enrollment
278
Locations
1
Primary Endpoint
The correlation between application of bedside ultrasound and differential diagnosis in shock patients
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

For the emergency physicians and critical care specialists, how to quickly recognize shock from diverse clinical features and immediately treat shock patients to prevent progression to irreversible organ dysfunction from initially reversible shock condition are important issues and challenges. In recent years, ultrasonography had been extensively used in clinical practice recently, and well-trained medical staffs can quickly and easily apply ultrasound to evaluate, examine, diagnose, and even treat the patients. The clinical application of point-of-care ultrasound can help the first-line physicians rapidly evaluate and diagnose the main symptoms and signs of the patients at bedside, and further initially stabilize and appropriately treat the patients subsequently. The aim of this program is to prospectively collection of the findings of point-of-care ultrasonography in shock patients at emergency room in NTUH. The clinical manifestations, and followed up the examinations, treatments, and prognosis will also be collected. The effect of bedside ultrasound on differential diagnosis and treatment of shock patients will be analyzed. The results of the current study can provide the base for further clinical trials and set up of shock team.

Detailed Description

Shock is defined as cellular and tissue hypoxia due to either reduced oxygen delivery, increased oxygen consumption, inadequate oxygen utilization, or a combination of these processes. According to the etiology about how it causes a decrease in blood flow to the cells and tissue, there are four types of shock naming cardiogenic shock, hypovolemic shock, obstructive shock, and distributive shock, respectively. The evaluation and management of shock patients is an extremely difficult challenge for the emergency physicians and critical care specialists. How to diagnose, classify, stabilize, and treat the shock patients quickly and in time are the arduous tasks. For the emergency physicians and critical care specialists, how to quickly recognize shock from diverse clinical features and immediately treat shock patients to prevent progression to irreversible organ dysfunction from initially reversible shock condition are important issues and challenges. In recent years, ultrasound instruments have gradually developed with higher radiographic quality and lower cost. Ultrasonography had been extensively used in clinical practice recently, and well-trained medical staffs can quickly and easily apply ultrasound to evaluate, examine, diagnose, and even treat the patients. The clinical application of point-of-care ultrasound can help the firstline physicians rapidly evaluate and diagnose the main symptoms and signs of the patients at bedside, and further initially stabilize and appropriately treat the patients subsequently. The aim of this program is to prospectively collection of the findings of point-of-care ultrasonography in shock patients at emergency room in NTUH. The clinical manifestations, and followed up the examinations, treatments, and prognosis will also be collected. The effect of bedside ultrasound on differential diagnosis and treatment of shock patients will be analyzed. The results of the current study can provide the base for further clinical trials and set up of shock team.

Registry
clinicaltrials.gov
Start Date
August 1, 2020
End Date
July 31, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • The shock patients in the emergency room at NTUH with one of the following conditions:
  • A clinician evaluated patients were with insufficient or improper tissue
  • Patients' systolic blood pressure \< 90mmHg or mean arterial pressure \< 65mmHg
  • Patients' laboratory data showed lactic acid \> 2.2 mmol/L

Exclusion Criteria

  • Age \< 20 years
  • Traumatic patients
  • Patients with DNR(Do Not Resuscitate) status

Outcomes

Primary Outcomes

The correlation between application of bedside ultrasound and differential diagnosis in shock patients

Time Frame: 6 month

The effect of bedside ultrasound on differential diagnosis and treatment of shock patients.

Study Sites (1)

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