Posterior Alpha Oscillations as an Index for the Attentional Bias in Children With Attentional Deficit Hyperactivity Disorder

Radboud University Medical Center1 site in 1 country60 target enrollmentNovember 2011

ConditionsADHD

Overview

Phase: N/A
Intervention: Not specified
Conditions: ADHD
Sponsor: Radboud University Medical Center
Enrollment: 60
Locations: 1
Primary Endpoint: Modualtion of alpha power
Status: Completed
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Investigate the hypothesis that children with ADHD have difficulty with the allocation of visio-spatial attention related to an inability to control posterior alpha brain oscillations. A paradigm will be used in which the aim is to address covert attention as similar recent studies did in adults with ADHD.

Registry

clinicaltrials.gov

Start Date

November 2011

End Date

January 2015

Last Updated

11 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Radboud University Medical Center

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•For both groups
•Age between 7 and 10 years of age.
•Estimated IQ above
•Psychopharmaca- naïve or -free.
•For the ADHD-group - A diagnosis of ADHD, classified by the DSM-IV.

Exclusion Criteria

•(Co-morbid) psychiatric disorder (major depression, bipolar disorder, psychotic disorder, chronically motor tic disorder or Gilles de la Tourette, Conduct disorder, autism spectrum disorder, eating disorder, anxiety disorder).
•Neurological disorders (e.g. epilepsy) currently or in the past.
•Cardiovascular disease currently or in the past.
•Serious motor or perceptual handicap.
•For the no ADHD-group
•No diagnosis of ADHD, classified by the DSM-IV.

Outcomes

Primary Outcomes

Modualtion of alpha power

Time Frame: Once for half an hour

Modulation\* of alpha power on congruent and incongruent trials of the covert attention task in 30 ADHD children and in 30 non-ADHD children \*Modulation is the (expected) cue-induced change by a covert attention task.

Secondary Outcomes

Mean deviation from middle on line bisection task(Once in about 5 minutes)
Inattention score on the ADHD-RS-IV(Once in about 10 minutes)
Standard deviation of response time on covert attention task(Once for half an hour)
Response time on covert attention task(Once for half an hour)
Hyperactivity/impulsivity score on the ADHD-RS-IV(Once in about 10 minutes)
Correct responses on covert attention task(Once for half an hour)