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Optimal Level of Occlusion Cuff Pressure for Determining Brachial Artery Flow Medieted dilation in Healthy Adults

Completed
Conditions
Healthy adults
Flow-mediated dilation, occlusion cuff pressure, pain sensation, healthy adults
Registration Number
TCTR20230822004
Lead Sponsor
President schoarship Chiangmai university
Brief Summary

The minimum occlusion pressure exceeded suprasystolic pressure by 25 mmHg which generated insignificant FMD response compared to the other two cuff pressures and caused minor pain, may be the most favorable pressure for determining FMD in healthy adults.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
12
Inclusion Criteria

healthy adults aged 20-40 years,
All participants were recreationally active (more than or equal to 600 metabolic equivalents (MET)-min per week), They were nonsmokers and normotensive (< 140/90 mmHg). Participants were without any diseases such as known cardiac or medical conditions, diabetes, cardiovascular disease, etc. None of the participants used any medications that interfere with the cardiovascular system .

Exclusion Criteria

Participants were excluded if they were unable to fully participate in the study.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Flow medieted dilation 3 times in a day Ulrasound machine
Secondary Outcome Measures
NameTimeMethod
Pain intensity every minute for five minutes during 5 minutes occlusion, and continuously recorded at 30-second intervals until the symptoms dissipated after cuff deflation. Numeric Pain Rating Scale ,Numbness every minute for five minutes during 5 minutes occlusion, and continuously recorded at 30-second intervals until the symptoms dissipated after cuff deflation. Visual Analog Scale
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