Comparison of hemodynamic profile of 0.5% hyperbaric Levobupivacaine and 0.5% hyperbaric Bupivacaine in patients undergoing Lower Limb Arthroscopic Surgeries under spinal anaesthesia, a prospective randomized control study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To compare the hemodynamic effects between 0.5% Hyperbaric Bupivacaine and 0.5% Hyperbaric Levobupivacaine
研究概览
简要总结
Subarachnoid blockade is a principal technique in lower extremity surgical anesthesia. This study primarily aims to provide a comprehensive analysis of the differences in hemodynamic stability between 0.5% hyperbaric Levobupivacaine and 0.5% hyperbaric Bupivacaine. Secondarily study anaesthetic efficacy, onset of sensory and motor blockade, patient recovery and overall surgical outcomes in elective lower limb surgeries. All these results can help make Subarachnoid blockade safer and tailor the drug as per requirement.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA Grade 1 and 2 Patients undergoing lower limb arthroscopic surgeries under spinal anaesthesia.
排除标准
- •Patients who are unwilling Known hypersensitivity to any of the test drug Any contraindication to spinal anaesthesia Cardiac arrythmias/ severe cardiac disease.
结局指标
主要结局
To compare the hemodynamic effects between 0.5% Hyperbaric Bupivacaine and 0.5% Hyperbaric Levobupivacaine
时间窗: Intraoperative hemodynamic parameters (BP, HR, and MAP) | will be assessed at 1 minute before (baseline) and 1, 2, 3, | and 5 minutes after the induction of spinal anesthesia. | Thereafter, measurements will be performed in 5-minute | intervals during the first 30 minutes of surgery and then | every 10 minutes until the end of the surgery.
次要结局
- 1.Duration of analgesia(2.Sensory and motor block onset)
研究者
Vikram C
Institute of Naval Medicine, INHS ASVINI