The efficacy of a non-invasive 1,060 nm diode laser for medial knee fat reductio

Completed

• Conditions: Medial knee fat; 1,060 nm Diode laser; fat reduction; medial knee

• Registration Number: TCTR20220219002
• Lead Sponsor: Faculty of Medicine Siriraj Hospital, Mahidol University

Brief Summary

Significant reduction in knee circumferences (p 0.001) at 1,3,6-month follow-up visits compared to baseline, and knee fat thickness measured by ultrasound in both axial and sagittal plane at 1 month and 6 months after treatment (p0.036 and p 0.001, respectively) were recorded. Side effects were mild and transient which included mild erythema and tenderness.

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-04-17
• Study Start: 2022-02-19
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 19

Inclusion Criteria

All female subjects complained of unwanted medial knee fat. Presenting with body mass index (BMI) of 18.5 to 30 kg/m2.

Exclusion Criteria

The subjects with the following conditions were excluded from the study: pregnant or lactating women, previous history of liposuction and surgical procedures, previous treatment of botulinum injections and laser procedures, immunosuppressive disorders such as human immunodeficiency virus (HIV) infections and malignancies, those who are taking immunosuppressant drugs, previous history of herpes virus infection, underlying psychological conditions, history of hypertrophic scar or keloid formation, history of any skin infections and skin hypersensitivity or photosensitivity reaction.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
mean kneecircumference baseline,1-month, 3-month, and 6-month follow-up visits after the treatment Direct measurement of knee circumference in cm

Secondary Outcome Measures

Name	Time	Method
fat layer thickness baseline,1-month, 3-month, and 6-month follow-up visits after the treatment ultrasound,subject satisfaction 1-month, 3-month, and 6-month follow-up visits after the treatment All subjects answered the percentage improvement scale survey at every follow-up visit.,Side effects evaluation after treatment,1-month, 3-month, and 6-month follow-up visits after the treatment observe side effect