Serrated Polyp Detection Rate Between Carbon Dioxide and Air Insufflation
- Conditions
- Serrated Polyp
- Interventions
- Procedure: Carbon dioxide insufflation colonoscopyProcedure: Air insufflation colonoscopy
- Registration Number
- NCT03623906
- Lead Sponsor
- The Catholic University of Korea
- Brief Summary
Sessile serrated adenomas are characterized by their flat shape and the presence of a yellow mucus cap overlying the lesion. These morphological features may account for their diagnostic difficulty during colonoscopy. Missed proximal sessile serrated adenomas are regarded as an important cause for interval cancers in the right colon and emphasize the importance of developing quality measures intended to enhance their detection. There is only one single-center retrospective cohort study on the impact of carbon dioxide insufflation on the detection of serrated polyps during colonoscopy. The investigators designed a randomized, controlled trial to compare the effect of carbon dioxide insufflation vs. room air insufflation on serrated polyp detection rate.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 1280
Patients 45-75-years-old who underwent a colonoscopy -
polyposis syndrome, Inflammatory bowel disease, previous colorectal operation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Carbon dioxide insufflation colonoscopy Carbon dioxide insufflation colonoscopy Carbon dioxide insufflation colonoscopy Air insufflation colonoscopy Air insufflation colonoscopy Room air insufflation colonoscopy
- Primary Outcome Measures
Name Time Method Serrated polyp detection rate 7 days
- Secondary Outcome Measures
Name Time Method