Effect of pitavastatin on increasing of high-density lipoprotein cholesterol and regression of carotid artery plaque.
Not Applicable
- Conditions
- hypercholesterolemia
- Registration Number
- JPRN-UMIN000002794
- Lead Sponsor
- Ogaki Municipal Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Not provided
Exclusion Criteria
1) HDL-C more than 100mg/dL. 2) Severe hypertensive patients. 3) History of cerebrovascular disease in 3 months before registration. 4) Severe renal dysfunction (creatinine>=2.0mg/dL) 5) Severe hepatic dysfunction. 6) Collagen disease. 7) Pregnant women, women suspected of being pregnant and lactating women or patients aiming to become pregnant during the clinical trial. 8) Without written informed consent. 9) Patients who are ineligible in the opinion of the investigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation between %change of high-density lipoprotein cholesterol and regression of carotid artery plaque.
- Secondary Outcome Measures
Name Time Method 1. Correlation between %change of LDL-C/ApoA1/hsCRP and regression of carotid artery plaque. 2. Incidence of major adverse cardiovascular events (MACE; defined as cardiac death, nonfatal myocardial infarction, unstable angina/cardiac failure/stroke / any other cardiac events required hospitalization). 3. Incidence of adverse effects.