Mesurement Of Optic Nerve Sheath Diameter In Patients Undergoing Lower Limb Surgeries Under Tourniquet During Central Neuraxial Blockade.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- The primary objective will be to study variation in optic nerve sheath diameter (ONSD)
研究概览
简要总结
The pneumatic tourniquet is commonly employed in lower limb surgery to improve surgical visibility, reduce blood loss, and minimize the risk of micro-emboli upon release. However, tourniquet inflation can lead to increased carbon dioxide levels, resulting in cerebral vasodilation and elevated intracranial pressure. Ultrasound measurement of the optic nerve sheath diameter (ONSD) has emerged as a non-invasive method capable of detecting rapid changes in intracranial pressure.
This study aims to investigate the impact of tourniquet inflation and deflation on optic nerve sheath diameter in patients undergoing lower limb surgeries under central neuraxial blockade, using ultrasound as a diagnostic tool.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of American Society of Anesthesiologists (ASA) physical status I and II of either sex aged 18-65 yrs, scheduled for elective lower limb surgery under central neuraxial blockade will be included in the study.
排除标准
- •Patients with presence of any one of the following will be excluded from the study
- •Refusal of consent
- •Patients having history of Cardiovascular dysfunction, Epilepsy or Pregnancy
- •Patients having history orbital trauma, optic nerve pathology, glaucoma.
- •Patient with increased ICP, coagulopathy and any contraindication to spinal anesthesia.
结局指标
主要结局
The primary objective will be to study variation in optic nerve sheath diameter (ONSD)
时间窗: 1. T0 - Baseline - before spinal anaesthesia | 2. T1 - just after tourniquet inflation | 3. T2 - just before tourniquet deflation | 4. T3 - 5 minutes after tourniquet deflation | 5. T4 - 10 minutes after tourniquet deflation
following tourniquet inflation and deflation.
时间窗: 1. T0 - Baseline - before spinal anaesthesia | 2. T1 - just after tourniquet inflation | 3. T2 - just before tourniquet deflation | 4. T3 - 5 minutes after tourniquet deflation | 5. T4 - 10 minutes after tourniquet deflation
次要结局
- 1) Correlation of ONSD with hemodynamic parameters.(2) Correlation of ONSD with PaCO2 levels after tourniquet deflation.)
研究者
Dr Suresh Kumar Singhal
PT. B.D Sharma,PGIMS Rohtak,HARYANA INDIA