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临床试验/NCT04959279
NCT04959279
暂停
不适用

A Pilot Randomized Controlled Trial of ED-TREAT (Early Detection and Treatment to Reduce Events With Agitation Tool) Compared to Usual Care

Yale University2 个研究点 分布在 1 个国家目标入组 26 人2026年4月1日

概览

阶段
不适用
干预措施
ED-TREAT
疾病 / 适应症
Psychomotor Agitation
发起方
Yale University
入组人数
26
试验地点
2
主要终点
Proportion of visits adherent to protocol
状态
暂停
最后更新
上个月

概览

简要总结

The purpose of this study is to conduct a a pilot trial that tests the acceptability, fidelity, and feasibility of ED-TREAT.

详细描述

This study will be a pilot RCT that compares ED-TREAT to usual care. The scientific premise of the proposed project is that an innovative EHR-embedded clinical decision support (CDS) tool can overcome the challenges to risk assessment and suggest pre-emptive use of behavioral techniques in the emergency setting. This would help clinicians appropriately invest resources to improve the quality of care for at-risk patients regardless of ultimate medical or psychiatric diagnoses and prevent agitation from occurring. This pilot trial will (1) test the integrity of the study protocol in preparation for a future full-scale RCT, (2) evaluate randomization protocols, (3) estimate rates of recruitment and retention, (4) assess acceptability and fidelity of the intervention, and (5) determine if the proposed effect size is reasonable. This registered study is actually the third aim of a larger study where the tool will be developed and assessed using observational data and input from a steering committee in aims 1 and 2 prior to pilot testing.

注册库
clinicaltrials.gov
开始日期
2026年4月1日
结束日期
2026年8月1日
最后更新
上个月
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

责任方
Sponsor

入排标准

入选标准

  • adult (age≥18) patients presenting to the YNHH ED during the pilot trial period
  • deemed to have a mild-moderate or high risk of agitation as determined by ED-TREAT
  • do not require physical restraint orders \<30 minutes of arrival
  • with a score of "4" (quiet and awake; normal level of activity) on the Behavioral Activity Rating Scale
  • have comfort with conversational English
  • able to provide verbal consent.

排除标准

  • 1\. Presence of a restraint order \<30 minutes of arrival and presence of a non-violent physical restraint order where indications are not due to agitation (e.g., for protecting intubation or life-preserving equipment)

研究组 & 干预措施

ED-TREAT

EHR-embedded clinical decision support (CDS) tool designed to overcome the challenges to risk assessment and suggest pre-emptive use of behavioral techniques in the emergency setting.

干预措施: ED-TREAT

Usual Care

结局指标

主要结局

Proportion of visits adherent to protocol

时间窗: 12 months

Proportion of visits in the intervention arm that are adherent to \>95% of the observational workflow checklist (primary outcome of fidelity)

次要结局

  • System usability scale(Baseline, 15 hours)

研究点 (2)

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