NCT04769557
Completed
Phase 4
Pre-emptive Analgesics for Additional Pain Relief in Impacted Third Molar Surgery by depositing4% Articaine With 1:200000 Epinephrine Using Vazirani-Akinosi Closed Mouth Technique- A Randomized Clinical Trial
Melaka Manipal Medical College1 site in 1 country60 target enrollmentMarch 4, 2017
Overview
- Phase
- Phase 4
- Intervention
- paracetamol
- Conditions
- Impacted Third Molar Tooth
- Sponsor
- Melaka Manipal Medical College
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- intraoperative pain
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The purpose of the study is to evaluate the efficacy of pre-emptive paracetamol in reducing intra operative pressure and post operative pain after surgical removal of impacted mandibular third molar using visual analogue scale
Investigators
Abdul Kalam Azad
Assistant Professor
Melaka Manipal Medical College
Eligibility Criteria
Inclusion Criteria
- •Patients aged 21 years and above
- •Healthy patients (ASA I)
- •Patients who are not allergic to the drugs and local anesthetic agents used
Exclusion Criteria
- •Patients who are on concurrent treatment with NSAIDs or corticosteroids
- •Patients with pericoronitis or periapical infection
Arms & Interventions
Paracetamol
Paracetamol
Intervention: paracetamol
Placebo
placebo
Intervention: Placebo
Outcomes
Primary Outcomes
intraoperative pain
Time Frame: during luxation of tooth
A 10 mm Visual Analogue Scale with higher score depicting severe pain
postoperative pain
Time Frame: 1 day
A 10 mm Visual analogue scale with higher score depicting severe pain
Secondary Outcomes
- Time to rescue medication(upto 360 minutes)
- number of patients taking rescue medications(Upto 360 minutes)
Study Sites (1)
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