NCT04769557CompletedPhase 4
Pre-emptive Analgesics for Additional Pain Relief in Impacted Third Molar Surgery by depositing4% Articaine With 1:200000 Epinephrine Using Vazirani-Akinosi Closed Mouth Technique- A Randomized Clinical Trial
Melaka Manipal Medical College1 site in 1 country60 target enrollmentStarted: March 4, 2017Last updated:
Conditions
Interventions
Drugs
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- intraoperative pain
Study Overview
Brief Summary
The purpose of the study is to evaluate the efficacy of pre-emptive paracetamol in reducing intra operative pressure and post operative pain after surgical removal of impacted mandibular third molar using visual analogue scale
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- Double (Participant, Care Provider)
Eligibility Criteria
- Ages
- 21 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Patients aged 21 years and above
- •Healthy patients (ASA I)
- •Patients who are not allergic to the drugs and local anesthetic agents used
Exclusion Criteria
- •Patients who are on concurrent treatment with NSAIDs or corticosteroids
- •Patients with pericoronitis or periapical infection
Arms & Interventions
Paracetamol
Experimental
Paracetamol
Intervention: paracetamol (Drug)
Placebo
Placebo Comparator
placebo
Intervention: Placebo (Drug)
Outcomes
Primary Outcomes
intraoperative pain
Time Frame: during luxation of tooth
A 10 mm Visual Analogue Scale with higher score depicting severe pain
postoperative pain
Time Frame: 1 day
A 10 mm Visual analogue scale with higher score depicting severe pain
Secondary Outcomes
- Time to rescue medication(upto 360 minutes)
- number of patients taking rescue medications(Upto 360 minutes)
Investigators
Abdul Kalam Azad
Assistant Professor
Melaka Manipal Medical College
Study Sites (1)
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