Pre Emptive Analgesics for Pain Relief in Impacted Lower Third Molar Surgery

Phase 4

Completed

• Conditions: Impacted Third Molar Tooth
• Interventions: Drug: paracetamol; Drug: Placebo

• Registration Number: NCT04769557
• Lead Sponsor: Melaka Manipal Medical College

Brief Summary

The purpose of the study is to evaluate the efficacy of pre-emptive paracetamol in reducing intra operative pressure and post operative pain after surgical removal of impacted mandibular third molar using visual analogue scale

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-04
• Primary Completion: 2019-02-27
• Study Completion: 2019-02-27
• Status Verified: 2021-02
• Study First Submitted: 2021-02-06
• Study First Submitted QC: 2021-02-21
• Last Update Submitted: 2021-02-21
• Study First Posted: 2021-02-24
• Last Update Posted: 2021-02-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients aged 21 years and above
• Healthy patients (ASA I)
• Patients who are not allergic to the drugs and local anesthetic agents used

Exclusion Criteria

• Patients who are on concurrent treatment with NSAIDs or corticosteroids
• Patients with pericoronitis or periapical infection

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Paracetamol	paracetamol	Paracetamol
Placebo	Placebo	placebo

Primary Outcome Measures

Name	Time	Method
intraoperative pain	during luxation of tooth	A 10 mm Visual Analogue Scale with higher score depicting severe pain
postoperative pain	1 day	A 10 mm Visual analogue scale with higher score depicting severe pain

Secondary Outcome Measures

Name	Time	Method
Time to rescue medication	upto 360 minutes	minutes
number of patients taking rescue medications	Upto 360 minutes	Total number of patients taking rescue medications

Trial Locations

Locations (1)

Melaka manipal medical college; 🇲🇾 Melaka, Malaysia