Acetaminophen

Generic Name: Acetaminophen

Brand Names: Acephen, Acetadryl, Allzital, Apadaz, Arthriten Inflammatory Pain, Bupap, Butapap, Cetafen, Children's Silapap, Coricidin Hbp Cold & Flu, Darvocet-N, Dayquil Sinex, Diphen, Dolofin, Dologen, Dologesic Reformulated Jun 2016, Duralgina, Dvorah, Endocet, Esgic, Exaprin, Excedrin, Excedrin PM Triple Action, Excedrin Tension Headache, Feverall, Fioricet, Fioricet With Codeine, Goody's Back & Body Pain Relief, Goody's Body Pain, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Hycet, Legatrin PM, Little Fevers, Lorcet, Lortab, Mapap, Mersyndol, Midol Complete, Midol Cramps & Bodyaches, Nalocet, Norco, Orbivan, Pamprin Max Formula, Pamprin Multi-symptom, Panadol, Pediacare Children's Fever Reducer Pain Reliever, Percocet, Percogesic Reformulated Jan 2011, Pharbetol, Premsyn Pms, Prolate, Rivacocet, Robaxacet, Robaxacet-8, Roxicet, Sudafed PE Sinus Headache, Tactinal, Tencon, Trezix, Triatec, Triatec-30, Triatec-8, Tylenol, Tylenol PM, Tylenol With Codeine, Ultracet, Vanatol, Vanatol S, Vanquish, Xodol, Xolox, Zamicet, Zflex, Zydone

Drug Type: Small Molecule

Chemical Formula: C_₈H_₉NO_₂

CAS Number: 103-90-2

Unique Ingredient Identifier: 362O9ITL9D

Background: Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA in 1951 and is available in a var...

Indication: In general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever. It is available over the counter in various forms, the most common being oral forms.
...

Associated Conditions: Acute Gouty Arthritis, Acute Musculoskeletal Pain, Allergic Reaction, Allergy to Tree Pollen, Ankylosing Spondylitis (AS), Chills, Cold, Common Cold, Cough, Cough caused by Common Cold, Coughing caused by Flu caused by Influenza, Dyskinesia of the Biliary Tract, Dyskinesia of the Urinary Tract, Febrile Convulsions, Febrile Illness Acute, Fever, Fibromyalgia, Flu caused by Influenza, Headache, Joint dislocations, Menstrual Distress (Dysmenorrhea), Mild pain, Muscle Inflammation, Muscle Injuries, Muscle Spasms, Musculoskeletal Pain, Myalgia, Nasal Congestion, Neuropathic Pain, Osteoarthritis (OA), Pain, Postoperative pain, Premenstrual cramps, Rheumatoid Arthritis, Rhinopharyngitis, Rhinorrhoea, Severe Pain, Sinusitis, Spasms, Spastic Pain of the Gastrointestinal Tract, Sprains, Symptoms Cold, Tension Headache, Toothache, Upper Respiratory Tract Infection, Whiplash Syndrome, Acute Torticollis, Articular inflammation, Cold or flu syndrome, Mild to moderate pain, Minor aches and pains, Minor pain, Moderate Pain, Moderate to severe pain

Associated Therapies: Airway secretion clearance therapy, Anti-spasmodics, Bronchodilation

Clinical Trials

Influence of HRS9531 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin in Healthy Subjects

Phase 1

Not yet recruiting

Conditions: Type 2 Diabetes

Interventions: Drug: Acetaminophen
Drug: Metformin
Drug: Warfarin
Drug: Atorvastatin
Drug: Digoxin
Drug: HRS9531

First Posted Date: 2024-12-09

Last Posted Date: 2024-12-09

Lead Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd.

Target Recruit Count: 57

Registration Number: NCT06723691

Locations: 🇨🇳
The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China

A Study of Efinopegdutide in Healthy Obese Participants (MK-6024-015)

Phase 1

Active, not recruiting

Conditions: Healthy

Interventions: Drug: Efinopegdutide
Drug: Placebo
Drug: Acetaminophen

First Posted Date: 2024-11-22

Last Posted Date: 2024-11-22

Lead Sponsor: Merck Sharp & Dohme LLC

Target Recruit Count: 48

Registration Number: NCT06701305

Locations: 🇺🇸
QPS-MRA, LLC (Site 0001), South Miami, Florida, United States

Pain After Strabismus Surgery

Phase 2

Not yet recruiting

Conditions: Strabismus

Interventions: Drug: Tylenol

First Posted Date: 2024-11-15

Last Posted Date: 2024-11-15

Lead Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Target Recruit Count: 80

Registration Number: NCT06689943

Locations: 🇺🇸
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States

Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial

Phase 4

Not yet recruiting

Conditions: Surgery
Pain, Post Operative

Interventions: Drug: NSAID
Drug: Opioid
Drug: Acetaminophen
Drug: Ibuprofen

First Posted Date: 2024-11-04

Last Posted Date: 2024-11-04

Lead Sponsor: University of Michigan

Target Recruit Count: 900

Registration Number: NCT06671002

Locations: 🇺🇸
Children's Hospital Los Angeles (CHLA), Los Angeles, California, United States
🇺🇸
Lucile Packard Children's Hospital Stanford, Palo Alto, California, United States
🇺🇸
University of Michigan, Ann Arbor, Michigan, United States

and more 1 locations

Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients

Phase 2

Recruiting

Conditions: Post Operative Analgesia
Bariatric Surgery
Bariatric Surgery (Gastric Bypass)
Bariatric Surgery Patients
Perioperative Analgesia

Interventions: Drug: Acetaminophen

First Posted Date: 2024-10-26

Last Posted Date: 2024-11-28

Lead Sponsor: Rutgers, The State University of New Jersey

Target Recruit Count: 150

Registration Number: NCT06658574

Locations: 🇺🇸
Robert Wood Johnson University Hospital, New Brunswick, New Jersey, United States

Intravenous Acetaminophen for Postoperative Delirium in Older Patients Recovering From Major Noncardiac Surgery

Phase 2

Not yet recruiting

Conditions: Delirium in Old Age

Interventions: Drug: Acetaminophen
Drug: Saline

First Posted Date: 2024-10-22

Last Posted Date: 2024-10-30

Lead Sponsor: RenJi Hospital

Target Recruit Count: 1930

Registration Number: NCT06653465

Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants

Phase 1

Recruiting

Conditions: Meningococcal Immunization
Healthy Volunteers

Interventions: Biological: Pentavalent Meningococcal ABCYW vaccine
Biological: MenACYW conjugate vaccine
Biological: Meningococcal group B vaccine
Drug: Paracetamol
Biological: DTap-HepB-IPV-Hib vaccine
Biological: Pneumococcal 13-valent conjugate vaccine
Biological: Rotavirus vaccine

First Posted Date: 2024-10-17

Last Posted Date: 2024-12-10

Lead Sponsor: Sanofi Pasteur, a Sanofi Company

Target Recruit Count: 750

Registration Number: NCT06647407

Locations: 🇭🇳
Investigational Site Number : 3400002, Tegucigalpa, Honduras
🇭🇳
Investigational Site Number : 3400003, Tegucigalpa, Honduras

Intravenous Acetaminophen After Cardiac Surgery - Definitive Study

Phase 4

Recruiting

Conditions: Post Operative Delirium
Post Operative Pain
Post-Op Complication
Post-cardiac Surgery

Interventions: Drug: acetaminophen

First Posted Date: 2024-09-25

Last Posted Date: 2024-09-25

Lead Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Target Recruit Count: 1100

Registration Number: NCT06613178

Locations: 🇨🇦
University of British Columbia, Vancouver, British Columbia, Canada
🇨🇦
University of Manitoba, Winnipeg, Manitoba, Canada
🇨🇦
Trillium Health Centre, Mississagua, Ontario, Canada

and more 5 locations