Acetaminophen
- Generic Name
- Acetaminophen
- Brand Names
- Acephen, Acetadryl, Allzital, Apadaz, Arthriten Inflammatory Pain, Bupap, Butapap, Cetafen, Children's Silapap, Coricidin Hbp Cold & Flu, Darvocet-N, Dayquil Sinex, Diphen, Dolofin, Dologen, Dologesic Reformulated Jun 2016, Duralgina, Dvorah, Endocet, Esgic, Exaprin, Excedrin, Excedrin PM Triple Action, Excedrin Tension Headache, Feverall, Fioricet, Fioricet With Codeine, Goody's Back & Body Pain Relief, Goody's Body Pain, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Hycet, Legatrin PM, Little Fevers, Lorcet, Lortab, Mapap, Mersyndol, Midol Complete, Midol Cramps & Bodyaches, Nalocet, Norco, Orbivan, Pamprin Max Formula, Pamprin Multi-symptom, Panadol, Pediacare Children's Fever Reducer Pain Reliever, Percocet, Percogesic Reformulated Jan 2011, Pharbetol, Premsyn Pms, Prolate, Rivacocet, Robaxacet, Robaxacet-8, Roxicet, Sudafed PE Sinus Headache, Tactinal, Tencon, Trezix, Triatec, Triatec-30, Triatec-8, Tylenol, Tylenol PM, Tylenol With Codeine, Ultracet, Vanatol, Vanatol S, Vanquish, Xodol, Xolox, Zamicet, Zflex, Zydone
- Drug Type
- Small Molecule
- Chemical Formula
- C8H9NO2
- CAS Number
- 103-90-2
- Unique Ingredient Identifier
- 362O9ITL9D
- Background
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA in 1951 and is available in a var...
- Indication
In general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever. It is available over the counter in various forms, the most common being oral forms.
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- Associated Conditions
- Acute Gouty Arthritis, Acute Musculoskeletal Pain, Allergic Reaction, Allergy to Tree Pollen, Ankylosing Spondylitis (AS), Chills, Cold, Common Cold, Cough, Cough caused by Common Cold, Coughing caused by Flu caused by Influenza, Dyskinesia of the Biliary Tract, Dyskinesia of the Urinary Tract, Febrile Convulsions, Febrile Illness Acute, Fever, Fibromyalgia, Flu caused by Influenza, Headache, Joint dislocations, Menstrual Distress (Dysmenorrhea), Mild pain, Muscle Inflammation, Muscle Injuries, Muscle Spasms, Musculoskeletal Pain, Myalgia, Nasal Congestion, Neuropathic Pain, Osteoarthritis (OA), Pain, Postoperative pain, Premenstrual cramps, Rheumatoid Arthritis, Rhinopharyngitis, Rhinorrhoea, Severe Pain, Sinusitis, Spasms, Spastic Pain of the Gastrointestinal Tract, Sprains, Symptoms Cold, Tension Headache, Toothache, Upper Respiratory Tract Infection, Whiplash Syndrome, Acute Torticollis, Articular inflammation, Cold or flu syndrome, Mild to moderate pain, Minor aches and pains, Minor pain, Moderate Pain, Moderate to severe pain
- Associated Therapies
- Airway secretion clearance therapy, Anti-spasmodics, Bronchodilation
Rectal Acetaminophen During Oocyte Retrievals
- Conditions
- Interventions
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2023-08-14
- Lead Sponsor
- University of South Florida
- Target Recruit Count
- 78
- Registration Number
- NCT05990868
Pre vs Post Block in Total Knee Arthroplasty (TKA)
- First Posted Date
- 2023-08-03
- Last Posted Date
- 2024-06-21
- Lead Sponsor
- University of Miami
- Target Recruit Count
- 84
- Registration Number
- NCT05974501
- Locations
- 🇺🇸
University of Miami, Miami, Florida, United States
Multimodal Pain Package vs. Regular Formulation for Pain Management in Ambulatory Spinal Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-07-28
- Last Posted Date
- 2024-06-21
- Lead Sponsor
- University of Miami
- Target Recruit Count
- 100
- Registration Number
- NCT05965492
- Locations
- 🇺🇸
university of Miami, Miami, Florida, United States
🇺🇸University of Miami, Miami, Florida, United States
Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft
- Conditions
- Interventions
- First Posted Date
- 2023-06-26
- Last Posted Date
- 2023-10-19
- Lead Sponsor
- Marquette University
- Target Recruit Count
- 50
- Registration Number
- NCT05919745
- Locations
- 🇺🇸
Marquette University School of Dentistry Graduate Periodontics Clinic, Milwaukee, Wisconsin, United States
Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma
- First Posted Date
- 2023-06-09
- Last Posted Date
- 2024-03-01
- Lead Sponsor
- Carl Ola Landgren, MD, PhD
- Target Recruit Count
- 30
- Registration Number
- NCT05896228
- Locations
- 🇺🇸
University of Miami, Miami, Florida, United States
A Study of Intravenous Acetaminophen for Small Bowel Obstruction
- First Posted Date
- 2023-05-26
- Last Posted Date
- 2024-07-29
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 18
- Registration Number
- NCT05878015
- Locations
- 🇺🇸
Mayo Clinic Florida, Jacksonville, Florida, United States
Morphine IV vs Paracetamol IV in Neonates and Infants After Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-05-10
- Last Posted Date
- 2023-05-10
- Lead Sponsor
- Erasmus Medical Center
- Target Recruit Count
- 208
- Registration Number
- NCT05853263
NSAID Use After Robotic Partial Nephrectomy
- Conditions
- Interventions
- First Posted Date
- 2023-05-03
- Last Posted Date
- 2024-10-08
- Lead Sponsor
- University of Miami
- Target Recruit Count
- 110
- Registration Number
- NCT05842044
- Locations
- 🇺🇸
University of Miami, Miami, Florida, United States
Treatment Of Fever In The Emergency Department
- Conditions
- First Posted Date
- 2023-04-14
- Last Posted Date
- 2023-04-14
- Target Recruit Count
- 324
- Registration Number
- NCT05814302
- Locations
- 🇮🇹
Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Roma, Italy
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Treatment in Spinal Surgery
- First Posted Date
- 2023-03-13
- Last Posted Date
- 2024-02-12
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT05764707
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.