Acetaminophen
- Generic Name
- Acetaminophen
- Brand Names
- Acephen, Acetadryl, Allzital, Apadaz, Arthriten Inflammatory Pain, Bupap, Butapap, Cetafen, Children's Silapap, Coricidin Hbp Cold & Flu, Darvocet-N, Dayquil Sinex, Diphen, Dolofin, Dologen, Dologesic Reformulated Jun 2016, Duralgina, Dvorah, Endocet, Esgic, Exaprin, Excedrin, Excedrin PM Triple Action, Excedrin Tension Headache, Feverall, Fioricet, Fioricet With Codeine, Goody's Back & Body Pain Relief, Goody's Body Pain, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Hycet, Legatrin PM, Little Fevers, Lorcet, Lortab, Mapap, Mersyndol, Midol Complete, Midol Cramps & Bodyaches, Nalocet, Norco, Orbivan, Pamprin Max Formula, Pamprin Multi-symptom, Panadol, Pediacare Children's Fever Reducer Pain Reliever, Percocet, Percogesic Reformulated Jan 2011, Pharbetol, Premsyn Pms, Prolate, Rivacocet, Robaxacet, Robaxacet-8, Roxicet, Sudafed PE Sinus Headache, Tactinal, Tencon, Trezix, Triatec, Triatec-30, Triatec-8, Tylenol, Tylenol PM, Tylenol With Codeine, Ultracet, Vanatol, Vanatol S, Vanquish, Xodol, Xolox, Zamicet, Zflex, Zydone
- Drug Type
- Small Molecule
- Chemical Formula
- C8H9NO2
- CAS Number
- 103-90-2
- Unique Ingredient Identifier
- 362O9ITL9D
- Background
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA in 1951 and is available in a var...
- Indication
In general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever. It is available over the counter in various forms, the most common being oral forms.
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- Associated Conditions
- Acute Gouty Arthritis, Acute Musculoskeletal Pain, Allergic Reaction, Allergy to Tree Pollen, Ankylosing Spondylitis (AS), Chills, Cold, Common Cold, Cough, Cough caused by Common Cold, Coughing caused by Flu caused by Influenza, Dyskinesia of the Biliary Tract, Dyskinesia of the Urinary Tract, Febrile Convulsions, Febrile Illness Acute, Fever, Fibromyalgia, Flu caused by Influenza, Headache, Joint dislocations, Menstrual Distress (Dysmenorrhea), Mild pain, Muscle Inflammation, Muscle Injuries, Muscle Spasms, Musculoskeletal Pain, Myalgia, Nasal Congestion, Neuropathic Pain, Osteoarthritis (OA), Pain, Postoperative pain, Premenstrual cramps, Rheumatoid Arthritis, Rhinopharyngitis, Rhinorrhoea, Severe Pain, Sinusitis, Spasms, Spastic Pain of the Gastrointestinal Tract, Sprains, Symptoms Cold, Tension Headache, Toothache, Upper Respiratory Tract Infection, Whiplash Syndrome, Acute Torticollis, Articular inflammation, Cold or flu syndrome, Mild to moderate pain, Minor aches and pains, Minor pain, Moderate Pain, Moderate to severe pain
- Associated Therapies
- Airway secretion clearance therapy, Anti-spasmodics, Bronchodilation
A Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen and Naproxen Sodium in Postoperative Dental Pain
- Conditions
- Interventions
- First Posted Date
- 2023-03-09
- Last Posted Date
- 2024-06-21
- Lead Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
- Target Recruit Count
- 447
- Registration Number
- NCT05761574
- Locations
- 🇺🇸
JBR Clinical Research LLC, Salt Lake City, Utah, United States
Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial
- Conditions
- Interventions
- First Posted Date
- 2023-02-10
- Last Posted Date
- 2024-11-01
- Lead Sponsor
- University of Michigan
- Target Recruit Count
- 900
- Registration Number
- NCT05722002
- Locations
- 🇺🇸
Temple University - Temple Health, Philadelphia, Pennsylvania, United States
🇺🇸University of Michigan, Ann Arbor, Michigan, United States
🇺🇸Henry Ford Health System, Detroit, Michigan, United States
Oral NSAI Versus Acetaminophen or Placebo as a Discharge Treatment of Non Complicated Renal Colics
- First Posted Date
- 2023-02-10
- Last Posted Date
- 2023-11-14
- Lead Sponsor
- University of Monastir
- Target Recruit Count
- 500
- Registration Number
- NCT05722782
- Locations
- 🇹🇳
Fattouma Bourguiba University Hospital, Monastir, Tunisia
A Study to Investigate Subcutaneous Isatuximab in Combination With Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma
- Conditions
- Interventions
- First Posted Date
- 2023-01-30
- Last Posted Date
- 2024-11-14
- Lead Sponsor
- Sanofi
- Target Recruit Count
- 74
- Registration Number
- NCT05704049
- Locations
- 🇦🇺
Investigational Site Number : 0360002, Wollongong, New South Wales, Australia
🇧🇷Hospital Mae de Deus Site Number : 0760002, Porto Alegre, Rio Grande Do Sul, Brazil
🇦🇺Investigational Site Number : 0360001, Fitzroy, Victoria, Australia
Simultaneous Versus Sequential Fractional CO2 Laser and Subcision Combination for Post-acne Atrophic Scars: A Split-face Comparative Study.
- Conditions
- Interventions
- Procedure: Simultaneous combination of fractional CO2 laser and subcisionProcedure: Sequential combination of fractional CO2 laser and subcisionDevice: Fractional CO2 laserProcedure: SubcisionDrug: Lidocaine/Prilocaine 2.5%-2.5% Topical Application CreamDrug: ParacetamolDrug: Lidocaine 2% Injectable Solution
- First Posted Date
- 2023-01-18
- Last Posted Date
- 2023-10-04
- Lead Sponsor
- Ho Chi Minh City Hospital of Dermato-Venereology
- Target Recruit Count
- 34
- Registration Number
- NCT05688202
- Locations
- 🇻🇳
Ho Chi Minh City Hospital of Dermato - Venereology, Ho Chi Minh City, Vietnam
Multi-Center Study of Naltrexone-Acetaminophen in Acute Migraine, With an Exploratory Analysis of Co-occurring Anxiety
- Conditions
- Interventions
- First Posted Date
- 2023-01-17
- Last Posted Date
- 2024-03-19
- Lead Sponsor
- Allodynic Therapeutics, Inc
- Target Recruit Count
- 300
- Registration Number
- NCT05685225
Intravenous Acetaminophen For Postoperative Pain in the Neonatal Intensive Care Unit
- First Posted Date
- 2023-01-10
- Last Posted Date
- 2023-04-25
- Lead Sponsor
- McMaster Children's Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT05678244
- Locations
- 🇨🇦
McMaster Children's Hospital, Hamilton, Ontario, Canada
Analgesic Effect of a New Analgesic Based Gel(Douloff) Versus Oral Paracetamol in Acute Soft Injuries
- First Posted Date
- 2022-12-12
- Last Posted Date
- 2023-05-16
- Lead Sponsor
- University of Monastir
- Target Recruit Count
- 1100
- Registration Number
- NCT05647681
Post-operative Pain Management in Children With Supracondylar Humerus Fractures
- Conditions
- Interventions
- First Posted Date
- 2022-12-07
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 100
- Registration Number
- NCT05640674
- Locations
- 🇺🇸
Texas Children's Hospital - West Campus, Houston, Texas, United States
🇺🇸Texas Children's Hospital - Woodlands Campus, Houston, Texas, United States
🇺🇸Texas Children's Hospital - Main Campus, Houston, Texas, United States
Efficacy of Acetaminophen-ibuprofen Combination on the Postoperative Pain After Thyroidectomy
- First Posted Date
- 2022-11-23
- Last Posted Date
- 2022-11-25
- Lead Sponsor
- The Catholic University of Korea
- Target Recruit Count
- 62
- Registration Number
- NCT05626010
- Locations
- 🇰🇷
Seoul St. Mary's Hospital, Seoul, Seocho-gu, Korea, Republic of
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.