Naproxen
- Generic Name
- Naproxen
- Brand Names
- Aleve, Aleve PM, Aleve-D, Anaprox, Naprelan, Naprosyn, Sallus, Sudafed Sinus & Pain, Treximet, Vimovo
- Drug Type
- Small Molecule
- Chemical Formula
- C14H14O3
- CAS Number
- 22204-53-1
- Unique Ingredient Identifier
- 57Y76R9ATQ
- Background
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its overall tolerability and effectiveness, nap...
- Indication
Naproxen is indicated for the management of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and for the relief of mild to moderate pain. Further, it is first-line therapy for osteoarthritis, acute gouty arthritis, dysmenorrhea, and musculoskelet...
- Associated Conditions
- Acute Gouty Arthritis, Acute Migraine, Ankylosing Spondylitis (AS), Back pain, Bursitis, Extra-Articular Rheumatism, Fever, Flu caused by Influenza, Headache, Juvenile Idiopathic Arthritis (JIA), Menstrual Distress (Dysmenorrhea), Migraine, Muscle Spasms, Nasal Congestion, Osteoarthritis (OA), Pain, Post Traumatic Pain, Postoperative pain, Primary Dysmenorrhoea, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Seasonal Allergic Rhinitis, Sinusitis, Tendinitis, Toothache, Articular inflammation
- Associated Therapies
- -
Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain
- Conditions
- Interventions
- First Posted Date
- 2023-08-16
- Last Posted Date
- 2024-10-10
- Lead Sponsor
- Laboratorios Liomont
- Target Recruit Count
- 58
- Registration Number
- NCT05995912
- Locations
- 🇲🇽
Oaxaca Site Management Organization, Oaxaca, Mexico
Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain
- Conditions
- Interventions
- First Posted Date
- 2023-08-08
- Last Posted Date
- 2024-08-07
- Lead Sponsor
- Dow University of Health Sciences
- Target Recruit Count
- 47
- Registration Number
- NCT05982392
- Locations
- 🇵🇰
Dow International Dental College, Karachi, Sindh, Pakistan
Duloxetine for LBP
- First Posted Date
- 2023-05-10
- Last Posted Date
- 2024-11-22
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 120
- Registration Number
- NCT05851976
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
A Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen and Naproxen Sodium in Postoperative Dental Pain
- Conditions
- Interventions
- First Posted Date
- 2023-03-09
- Last Posted Date
- 2024-06-21
- Lead Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
- Target Recruit Count
- 447
- Registration Number
- NCT05761574
- Locations
- 🇺🇸
JBR Clinical Research LLC, Salt Lake City, Utah, United States
A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
- Conditions
- Interventions
- First Posted Date
- 2022-06-09
- Last Posted Date
- 2024-03-13
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 40
- Registration Number
- NCT05411718
- Locations
- 🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States
Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Naproxen, Aceclofenac, Celecoxib and Ilaprazole
- Conditions
- Interventions
- First Posted Date
- 2022-02-14
- Last Posted Date
- 2023-06-28
- Lead Sponsor
- Il-Yang Pharm. Co., Ltd.
- Target Recruit Count
- 72
- Registration Number
- NCT05237297
- Locations
- 🇰🇷
Severance Hospital, Seoul, Korea, Republic of
Novel Non-opioid Post-surgical Pain Treatment in Females
- First Posted Date
- 2021-10-21
- Last Posted Date
- 2024-03-18
- Lead Sponsor
- Northwestern University
- Registration Number
- NCT05087914
- Locations
- 🇺🇸
Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients
- Conditions
- Interventions
- First Posted Date
- 2021-01-05
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- Hersh, Elliot V., DMD, MS, PhD
- Target Recruit Count
- 30
- Registration Number
- NCT04694300
- Locations
- 🇺🇸
University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, United States
Pharmacokinetic Interaction Between Tegoprazan and NSAIDs After Multiple Oral Dosing in Healthy Male Volunteers
- Conditions
- Interventions
- First Posted Date
- 2020-11-23
- Last Posted Date
- 2020-11-23
- Lead Sponsor
- HK inno.N Corporation
- Target Recruit Count
- 60
- Registration Number
- NCT04639804
- Locations
- 🇰🇷
Chonbuk National University Hospital, Jeonju, Korea, Republic of
Drug-drug Interaction Between DWP14012 and Three Different Kinds of NSAIDs
- Conditions
- Interventions
- First Posted Date
- 2020-07-29
- Last Posted Date
- 2020-07-29
- Lead Sponsor
- Daewoong Pharmaceutical Co. LTD.
- Target Recruit Count
- 110
- Registration Number
- NCT04490434
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
Drug Development Updates
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