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Fish, Polyunsaturated Fatty Acids Intake and Type 2 Diabetes

Completed
Conditions
Type2 Diabetes
Registration Number
NCT03259321
Lead Sponsor
Zhejiang University
Brief Summary

The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of type 2 diabetes (T2D) is heavily debated but evidence from large populations in China is scant. The investigators aim to use data from the China Health and Nutrition Survey (CHNS) to assess the long-term association between fish, PUFA intake and T2D risk.

Detailed Description

The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of T2D is heavily debated but evidence from large populations in China is still lacking. The investigators aim to utilize data from China Health and Nutrition Survey (CHNS, 1997-2011). The investigators will calculate cumulative means of fish and PUFA intake based on 3-day food records in each wave. Sex-specific Cox regression models will be used to estimate relative risk of T2D. Results from this work will provide epidemiological evidence for improving recommendations on fish and PUFA intake for Chinese in dietary guidelines.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
15100
Inclusion Criteria
  • Adults aged ≥20 with complete data on diet and follow-up time
Exclusion Criteria
  • Missing information for Type 2 diabetes
  • Type 2 diabetes
  • Cardiovascular disease

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Type 2 diabetesFrom entry into the study (baseline: 1997-2009) until 2011

Incidence of type 2 diabetes, on basis of self-reported physician diagnosis, fasting plasma glucose ≥ 7.0 mmol/l or HbA1c ≥ 6.5%

Secondary Outcome Measures
NameTimeMethod
Fish and polyunsaturated fatty acids intakeFrom entry into the study (baseline: 1997-2009) until 2011

Cumulative averages of fish and PUFA intake based on 3-day 24-hr recall in each wave

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