External Oblique Intercostal Nerve Block versus Epidural in Live Open Donor Hepatectomy- A Randomised Controlled Trial
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare postoperative fentanyl consumption at 48 hours between the two groups.
研究概览
简要总结
Living donor liver transplantation is a definitive treatment for end stage liver disease patients. Postoperative pain is an important cause of morbidity in the donor population.
Pain in donor hepatectomy is multifactorial due to large subcostal incision, rib retraction, diaphragmatic irritation or of visceral origin.This can have a significant negative impact on the quality of life of the donor.
There are various modalities for pain treatment in donors. Epidural is the standard of care. Thoracic epidural analgesia provides efficient intraoperative and postoperative analgesia following donor hepatectomy.
The effectiveness of the block has been shown in many literatures and is considered relatively safe to perform, as compared to other regional technique.However due to concerns of postoperative coagulopathy, the procedure has concerns.
USG guided abdominal wall blocks are generally easy to apply, reliable and are alternatives to epidural analgesia.They can be easily performed with the patient in the supine position.
US guided External Oblique Intercostal block is an emerging technique, which blocks anterior and lateral cutaneous branches of the thoracoabdominal nerves and has been used successfully in upper abdominal surgeries for perioperative analgesia.
Till now there are no studies in EOI block in patients undergoing hepatectomy.
In this study we aim to compare ultrasound guided continuous bilateral EOI block and continuous thoracic epidural analgesia for pain management in donor hepatectomy
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •All adult patients aged
- •60 years, undergoing open live donor hepatectomy.
排除标准
- •Patient refusal Contraindication to neuraxial anesthesia Allergy to local anesthetics Insufficient comprehension to use of IVPCA.
结局指标
主要结局
To compare postoperative fentanyl consumption at 48 hours between the two groups.
时间窗: To compare postoperative fentanyl consumption at 48 hours between the two groups.
次要结局
- To compare the intraoperative IV fentanyl requirements in both groups(To compare the time of first rescue analgesia requirement in both the groups)
研究者
Dr Rachana C Nair
Institute of Liver and Biliary Sciences