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Clinical Trials/CTIS2024-512077-27-00
CTIS2024-512077-27-00
Active, not recruiting
Phase 1

EVALUATION OF THE EFFICACY OF INHALATORY SEDATION IN COMPARISON WITH CONVENTIONAL INTRAVENOUS SEDATION IN NEUROCRITIC PATIENTS - NEURO-CONDA

Hospital Universitari De Girona Doctor Josep Trueta0 sites24 target enrollmentFebruary 21, 2024

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
EUROCRITIC PATIENTS
Sponsor
Hospital Universitari De Girona Doctor Josep Trueta
Enrollment
24
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
February 21, 2024
End Date
TBD
Last Updated
last year
Study Type
Interventional clinical trial of medicinal product
Sex
All

Investigators

Sponsor
Hospital Universitari De Girona Doctor Josep Trueta

Eligibility Criteria

Inclusion Criteria

  • Patients equal or older than 18 years old, Neurocritical patients (intracranial hemorrhage, severe traumatic brain injury, ischemic or hemorrhagic stroke) who, due to their clinical situation and by decision of the treating physician, require advanced neurological monitoring (ICP catheter, DTC...) and deep sedation Intensive Unit Care admission, Informed consent form signed by a family member/legal representative

Exclusion Criteria

  • Neurocritical patients with risk of CTEH (by imaging techniques) who do not have ICP catheter monitoring, End\-of\-life situation or with ICU admission oriented towards donation, Refusal to informed consent by the relative/legal representative of reference., Neurocritical patients monitored with an ICP catheter but with initial values \>20 mmHg, Neurocritical patients with decompressive craniectomy monitored with an ICP catheter and with initial values ??\>13 mmHg., Severe hypoxemia (pO2\<60mmHg) or high FiO2 requirements (\>0\.6\) and/or high PEEP values (\>10mmHg)., Patients in shock who require vasoactive support with noradrenaline \>0\.5mcg/kg/min and/or lactate \>2\. 5mmol/L., Patients who, upon admission, in the initial neurological evaluation with transcranial Doppler, have a negative Giller Test (loss of cerebral self\-regulation)., Patients under 18 years of age., Pregnant or breastfeeding patients., Patients with any contraindication to the administration of isoflurane

Outcomes

Primary Outcomes

Not specified

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