Change in disability in activities of daily living over time among adults with advanced respiratory disease during the COVID-19 pandemic

Not Applicable

Completed

• Conditions: Exploring disability in patients with non-small cell lung cancer or respiratory disease; Respiratory

• Registration Number: ISRCTN14159936
• Lead Sponsor: King's College Hospital NHS Foundation Trust

Brief Summary

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34382888/ (added 04/01/2024)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-12-14
• Study Completion: 2021-08-01
• Last Update Posted: 15 January 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Patients aged >18 years
2. Advanced lung cancer or respiratory disease as defined by one of the following:
2.1. Lung cancer: Inoperable stage III or IV non-small cell lung cancer
2.2. Chronic Obstructive Lung Disease (COPD): Severe or very severe stages of COPD according to the criteria set by the Global Initiative for Chronic Obstructive Lung Disease (GOLD): stage III (FEV1/FVC <70%. 30% = FEV1 <50% predicted with or without chronic symptoms (cough, sputum production)) and stage IV (FEV1/FVC <70%. FEV1 <30% predicted plus chronic respiratory failure)
2.3. Interstitial lung disease (ILD): Carbon monoxide transfer factor (TLCO/DLCO) level of <40% or FVC <50% predicted
3. Patients with capacity to consent
4. Patients with ability to understand and complete a questionnaire in English
5. Life expectancy of >1 month as assessed by the person taking consent

Exclusion Criteria

1. Patients aged <18 years
2. Patients who lack the capacity to consent
3. Patients who lack the ability to understand and complete a questionnaire in English
4. Life expectancy of <1 month as assessed by the person taking consent

Study & Design

• Study Type: Observational
• Study Design: Not specified