Single Lung Ventilation Versus Two Lung Ventilation

Not Applicable

• Conditions: Hypoxemia; Single Lung Ventilation
• Interventions: Procedure: Single lung ventilation by double lumen endotracheal tube; Procedure: Two lung ventilation by conventional single lumen endotracheal tube

• Registration Number: NCT04981990
• Lead Sponsor: Ain Shams University

Brief Summary

Hypoxia in single lung ventilation versus two lung ventilation in video assisted lung surgeries

Detailed Description

Incidence of hypoxia in single lung ventilation by double lumen endotracheal tube "of choice in lung surgeries" versus incidence of hypoxia in two lung ventilation by conventional single lumen endotracheal tube "intermittent two lung ventilation"

Study Timeline

• Study Start: 2021-03-01
• Study First Submitted: 2021-04-22
• Study First Submitted QC: 2021-07-19
• Study First Posted: 2021-07-29
• Status Verified: 2021-08
• Last Update Submitted: 2021-08-24
• Primary Completion: 2021-08-25
• Study Completion: 2021-08-25
• Last Update Posted: 2021-08-25

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Age group: Adult patients from age of 21 years to 60 years
• Sex: Both sexes
• ASA Classification: patients with ASA classification II, III.
• Elective lung surgeries using video assisted thoracoscopic surgeries.

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Exclusion Criteria

• Patients refuse to give informed consent.
• ASA Classification: ASA IV.
• Failure of thoracoscopic surgeries and continue as open thoracotomy
• Patients with ischemic heart diseases, where hypoxemia might be preexisting, or patient be more vulnerable to hypoxemia whatever the technique or time of hypoxia.
• Emergency lung surgeries.
• Patients underwent previous lung surgeries of any cause.
• Patients with pathology to the non-operated side.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Single lung ventilation	Single lung ventilation by double lumen endotracheal tube	Using double lumen endotracheal tube and lung isolation
Two lung ventilation	Two lung ventilation by conventional single lumen endotracheal tube	Using conventional single lumen endotracheal tube and intermittent two lung ventilation

Primary Outcome Measures

Name	Time	Method
Incidence of hypoxemia	Intraoperative to first 24 hours post operative	Hypoxemia in single and two lung ventilation by serial arterial blood gases

Secondary Outcome Measures

Name	Time	Method
Incidence of failure to correct Hypoxemia in single lung ventilation	Intraoperative	Stop lung isolation and procedure using two lung ventilation to correct hypoxia
Incidence of failure of two lung ventilation to create optimum surgical field	Intraoperative	Frequent stopping of ventilation and the surgent can't access the surgical field easily
Incidence of post operative complications	First 24 hours post operative	Any associated complications

Trial Locations

Locations (1)

Aun Shams University Hospitals; 🇪🇬 Cairo, Egypt