Effects of Two Different Ventilation Modes Used in Gynecologic Laparoscopic Operations Performed in Steep Trendelenburg Position on Hemodynamic Parameters
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Respiration, Artificial
- Sponsor
- Ufuk University
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Measurement of changes in MAP
- Last Updated
- 7 years ago
Overview
Brief Summary
Different ventilation modes can be used in laparoscopic surgeries. These surgeries are performed in steep Trendelenburg position with serious hemodynamic disturbances. This study aims to observe the hemodynamic effects of two different ventilation modes in laparoscopic gynecologic surgery performed in steep Trendelenburg position.
Investigators
Hakan Yılmaz
Associate Professor
Ufuk University
Eligibility Criteria
Inclusion Criteria
- •Women of ASA I and II classification between 18-65 years scheduled for elective gynecologic laparoscopic surgery
Exclusion Criteria
- •Patient refusal to participate
- •Patients with severe cardiac (congestive heart failure etc) and pulmonary (COPD, pulmonary hypertension) disease (ASA \> III)
- •Morbid obesity
- •Negative Allen test
Outcomes
Primary Outcomes
Measurement of changes in MAP
Time Frame: T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation
Mean arterial pressure (MAP) (mmHg)
Measurement of changes in heart rate
Time Frame: T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation
Heart rate (bpm)
Measurement of changes in systemic vascular resistance index
Time Frame: T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation
Systemic vascular resistance index (dyne x sec/cm2)
Measurement of changes in stroke volume index
Time Frame: T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation
Stroke volume index (mL/m2)
Measurement of changes in cardiac index
Time Frame: T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation
Cardiac index L(min x m2)
Measurement of changes in stroke volume variation
Time Frame: T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation
Stroke volume variation (%)
Measurement of changes in cardiac cycle efficiency
Time Frame: T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation
Cardiac cycle efficiency (units)
Measurement of changes in aortic dp/dt
Time Frame: T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation
Aortic dP/dt (mmHg/msec)
Secondary Outcomes
- Measurement of changes in peak airway pressure(T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation)
- Measurement of changes in mean airway pressure(T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation)
- Measurement of changes in plateau airway pressure(T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation)