The Effects of Different Ventilation Modes on Patients With Plasma Inflammatory Factor and Respiratory Function in Patients With Pulmonary Lobe Resection
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lung Injury
- Sponsor
- Mao Enting
- Enrollment
- 102
- Locations
- 1
- Primary Endpoint
- Clinical Pulmonary Infection Score
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
The objective of this study was to discuss the effects of different ventilation modes on patients with plasma inflammatory factor and respiratory function in patients with pulmonary removal.
Detailed Description
Patients who meet the inclusion criteria will be numbered in the order of admission, and a dedicated person will prepare codes and opaque envelopes for random allocation. This study was divided into 3 groups, one groups was ventilation side volume control ventilation+continuous positive pressure ventilation on the non ventilation side, the other groups was ventilation side volume control ventilation+continuous positive pressure ventilation on the non ventilation side; the other groups was ventilation side pressure regulated volume control ventilation+continuous positive pressure ventilation on the non ventilation side.
Investigators
Mao Enting
Anesthesiology resident,Affiliate Hospital of Zunyi Medical University
Zunyi Medical College
Eligibility Criteria
Inclusion Criteria
- •Comprehensive examination and analysis of imaging, laboratory examination and other comprehensive examinations, the diagnosis is clear, which is in line with lobe resection surgical indications
- •Age 18-75 years old, the gender is not limited;
- •ASA grading Ⅰ \~ III level;
- •It is expected that the single lung ventilation time is ≥1 hours, and ≤3 hours
Exclusion Criteria
- •Emergency surgery;
- •There is a taboos on the existence of systemic anesthesia;
- •There is a history of acute chronic upper respiratory infections in the past January;
- •Previous bronchial asthma, chronic obstructive pulmonary disease, bronchial dilatation, phthisis ,aspergillosis , acute respiratory distress syndrome or history of respiratory failure;
- •Merge the function of important organs such as heart, liver, and kidney;
- •There was a history of chest surgery and the history of trauma;
- •Preoperative lung function test obvious abnormal abnormal abnormalities (1 second of exhalation (FEV1) \<60%);
- •Patients refuse to participate in the clinical trial
Outcomes
Primary Outcomes
Clinical Pulmonary Infection Score
Time Frame: Within 15 days after surgery
The clinical pulmonary infection score index is mainly used to evaluate the severity of pulmonary infection, which involves many factors, including: body temperature, white blood cell count, tracheal secretions, oxygenation, X-ray chest X-ray, and the progress of pulmonary infiltrates. The maximum score is 12 points, and the severity of infection is directly proportional to its score.