跳至主要内容
临床试验/NCT02117037
NCT02117037已完成不适用

Prognostic Value of Biomarkers Associated With Endothelial Progenitor Cells Mobilization in Acute Coronary Syndromes

Assistance Publique Hopitaux De Marseille2 个研究点 分布在 1 个国家目标入组 180 人开始时间: 2014年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
180
试验地点
2
主要终点
evaluate the value of circulating endothelial progenitor cells quantification in the initial phase of ACS in predicting the occurrence of a major cardiovascular event (ECVM ) at 1 year.

研究概览

简要总结

This prospective study aimed to validate a new prognostic approach of endothelial progenitor cells associated biomarkers in patients with acute coronary syndromes . Recruitment is made prospectively by two centers of Inter -region South Mediterranean,

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • acute coronary syndrome (ST + < 12 hours and ST- high risk or intermediate risk ),which there is an indication of percutaneous coronary intervention.

排除标准

  • Chronic inflammatory disease
  • Infectious disease
  • Erythrocyte <4 G/l
  • Thrombopénia less than 100 000/mm3 ;

研究组 & 干预措施

study of PEC markers and chemokines/ chemokine recep

Other

blood sample for dosage and study of PEC markers and chemokines/ chemokine receptors

干预措施: blood sample (Other)

结局指标

主要结局

evaluate the value of circulating endothelial progenitor cells quantification in the initial phase of ACS in predicting the occurrence of a major cardiovascular event (ECVM ) at 1 year.

时间窗: one year

次要结局

  • determine the technical characteristics (sensitivity and specificity) and predictive value of the number of PEC(one day , one month , one year)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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