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Prognostic Value of Biomarkers Associated With Endothelial Progenitor Cells Mobilization in Acute Coronary Syndromes

Not Applicable
Completed
Conditions
Acute Coronary Syndromes
Interventions
Other: blood sample
Registration Number
NCT02117037
Lead Sponsor
Assistance Publique Hopitaux De Marseille
Brief Summary

This prospective study aimed to validate a new prognostic approach of endothelial progenitor cells associated biomarkers in patients with acute coronary syndromes . Recruitment is made prospectively by two centers of Inter -region South Mediterranean,

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
180
Inclusion Criteria
  • acute coronary syndrome (ST + < 12 hours and ST- high risk or intermediate risk ),which there is an indication of percutaneous coronary intervention.
Exclusion Criteria
  • Cancer
  • Chronic inflammatory disease
  • Infectious disease
  • Erythrocyte <4 G/l
  • Thrombopénia less than 100 000/mm3 ;

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
study of PEC markers and chemokines/ chemokine recepblood sampleblood sample for dosage and study of PEC markers and chemokines/ chemokine receptors
Primary Outcome Measures
NameTimeMethod
evaluate the value of circulating endothelial progenitor cells quantification in the initial phase of ACS in predicting the occurrence of a major cardiovascular event (ECVM ) at 1 year.one year
Secondary Outcome Measures
NameTimeMethod
determine the technical characteristics (sensitivity and specificity) and predictive value of the number of PECone day , one month , one year

Trial Locations

Locations (1)

assistance Publique Hopitaux de Marseille

🇫🇷

Marseille, France

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