Effect of Intrathecal Morphine in Children Undergoing Major Abdominal Surgeries,
- Registration Number
- NCT03158584
- Lead Sponsor
- Assiut University
- Brief Summary
safety and efficacy of intrathecal morphine in post operative pain relief in pediatric patients undergoing major abdominal cancer surgeries using different doses of intrathecal morphine (2 μg/kg , 5 μg/kg ,10 μg/kg).
- Detailed Description
After obtaining approval of the local ethics committee of faculty of medicine, Assiut University , Assiut , Egypt , and parent's written informed consent, This randomized double -blinded prospective study conducted on ( 45 ) pediatric patients aged 3-12 years , weighting between 10-30 kg , and of American Society of Anesthesiologists (ASA) physical status I and II scheduled for major abdominal surgeries
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 45
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description morphine 2 μg/kg Intrathecal Morphine Children will receive intrathecal morphine 2 μg/kg in 2 ml volume normal saline. morphine 5 μg/kg Intrathecal Morphine Children will receive intrathecal morphine 5 μg/kg in 2 ml volume normal saline. morphine 10 μg/kg Intrathecal Morphine Children will receive intrathecal morphine 10 μg/kg in 2 ml volume normal saline.
- Primary Outcome Measures
Name Time Method visual analog scale 24 hours postoperative . 0- 10 in cm score range will be used to assess pain
- Secondary Outcome Measures
Name Time Method rams y sedation score 24 hours 0-4 score will be used
Trial Locations
- Locations (1)
South Egypt Cancer Institute
🇪🇬Assiut, Egypt