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Morphine

Generic Name
Morphine
Brand Names
Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
Drug Type
Small Molecule
Chemical Formula
C17H19NO3
CAS Number
57-27-2
Unique Ingredient Identifier
76I7G6D29C

Overview

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorphone, meperidine, and oxycodone. Morphine was granted FDA approval in 1941.

Background

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorphone, meperidine, and oxycodone. Morphine was granted FDA approval in 1941.

Indication

Morphine is used for the management of chronic, moderate to severe pain. Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.

Associated Conditions

  • Chronic Pain
  • Severe Pain

FDA Approved Products

Morphine Sulfate
Manufacturer:Cantrell Drug Company
Route:INTRAVENOUS
Strength:1 mg in 1 mL
Approved: 2014/10/20
NDC:52533-059
MORPHINE SULFATE
Manufacturer:SpecGx LLC
Route:ORAL
Strength:15 mg in 1 1
Approved: 2023/01/30
NDC:0406-8315
Morphine Sulfate
Manufacturer:Hikma Pharmaceuticals USA Inc.
Route:INTRAVENOUS
Strength:10 mg in 1 mL
Approved: 2024/02/01
NDC:0641-6127
Morphine Sulfate Extended Release
Manufacturer:Major Pharmaceuticals
Route:ORAL
Strength:100 mg in 1 1
Approved: 2019/01/03
NDC:0904-6560
Morphine Sulfate
Manufacturer:Hikma Pharmaceuticals USA Inc.
Route:INTRAVENOUS
Strength:8 mg in 1 mL
Approved: 2024/02/01
NDC:0641-6126

Singapore Approved Products

MST CONTINUS TABLET 10 mg
Manufacturer:BARD PHARMACEUTICALS LTD
Form:TABLET, FILM COATED
Strength:10 mg
Online:Yes
Approved: 1991/03/04
Approval:SIN05506P
MORPHINE SULFATE KALCEKS SOLUTION FOR INJECTION 10MG/ML
Manufacturer:HBM Pharma s.r.o.
Form:INJECTION, SOLUTION
Strength:10.00mg/mL
Online:Yes
Approved: 2023/10/20
Approval:SIN16891P
DBL MORPHINE SULFATE INJECTION BP 10 mg/ml
Manufacturer:Siegfried Hameln GmbH
Form:INJECTION
Strength:10 mg/ml
Online:Yes
Approved: 1988/05/04
Approval:SIN00757P
ORAMORPH SYRUP 2MG/ML
Manufacturer:L.MOLTENI & C.DEI F.LLI ALITTI SOCIETA' DI ESERCIZIO S.P.A.
Form:SYRUP
Strength:2MG/ML
Online:Yes
Approved: 2020/10/30
Approval:SIN16036P
Morphine-hameln 10 mg/ml Injection
Manufacturer:Siegfried Hameln GmbH
Form:INJECTION, SOLUTION
Strength:10mg
Online:Yes
Approved: 2009/02/09
Approval:SIN13598P

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