The ACOVID-19 Study - A Prospective Cohort Study Investigating the Acute Effect of COVID-19 on the Heart by Continuous ECG Monitoring
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Herlev and Gentofte Hospital
- Enrollment
- 1,000
- Locations
- 1
- Primary Endpoint
- Incident intensive care unit admission during hospitalization and a confirmed COVID-19 diagnosis
Study Overview
Brief Summary
The study is a prospective clinical cohort study of consecutive patients hospitalized at all hospitals of greater Copenhagen with a laboratory confirmed diagnosis of COVID-19. The investigators aim to examine if continuous ECG monitoring can be used to understand the contribution of COVID-19 infection in the acute phase to the development of cardiac arrhythmias, especially focusing on cardiovascular outcomes. In all patients included, the investigators aim to examine if continuous ECG monitoring - alone and in combination with biomarkers - can be used to detect early signs of cardiac complications and predict long-term risk of cardiovascular morbidity and mortality following COVID-19 infection.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •All patients hospitalized at hospitals of greater Copenhagen area and Zealand with a laboratory confirmed diagnosis of COVID-19 > 18 years of age.
Exclusion Criteria
- •Persons not able to cooperate
- •Persons unable to understand and sign "informed consent"
Outcomes
Primary Outcomes
Incident intensive care unit admission during hospitalization and a confirmed COVID-19 diagnosis
Time Frame: 4 months
In-hospital mortality during hospitalization and a confirmed COVID-19 diagnosis
Time Frame: 4 months
Secondary Outcomes
- Incident pulmonary embolism during hospitalization and a confirmed COVID-19 diagnosis(4 months)
- Incident cardiac arrest during hospitalization and a confirmed COVID-19 diagnosis(4 months)
- Incident hypoxic respiratory failure during hospitalization and a confirmed COVID-19 diagnosis(4 months)
Investigators
Morten Lamberts
Associate Professor and Research Director
Herlev and Gentofte Hospital