Prognostic Factors Impacting Surgical Resection Outcomes in Patients With Brain
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Functional outcome of patients undergoing surgery for brain metastasis
Study Overview
Brief Summary
While many studies have investigated the prognostic factors for patients undergoing surgical resection for primary brain tumors, decision-making for patients with brain metastasis (BM) is more complex because of their higher burden of comorbidities compared to those with primary brain tumors. In addition, although various prognostic indicators have been identified to predict prognosis in several types of cancer, such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), prognostic nutritional index (PNI), and systemic immune-inflammation index (SII), limited studies have yet determined which group of patients would yield beater survival outcome after surgical resection for BM. This study aimed to investigate the impact of patient and perioperative characteristics and prognostic indicators on survival outcome of patients undergoing surgical resection of BM.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients with Clinical diagnosis of brain metastasis
- •patients who underwent craniotomy surgery for brain metastasis
Exclusion Criteria
- •patients with insufficient data for associated factors
- •patients who underwent stereotactic biopsy for brain metastasis
- •patients who did not undergo craniotomy surgery for brain metastasis
Outcomes
Primary Outcomes
Functional outcome of patients undergoing surgery for brain metastasis
Time Frame: from date of surgery until 6 months after surgery ordate of death from any cause, whichever came first
change of preoperative and postoperative modified rankin scale
survival outcome of patients undergoing surgery for brain metastasis
Time Frame: From date of surgery until the date of death from any cause, whichever came first, assessed up to 100 months
overall survival of patients
Secondary Outcomes
No secondary outcomes reported