Surgical Resection Outcomes in Patients With Brain Metastasis

Recruiting

• Conditions: Brain Metastases

• Registration Number: NCT06318065
• Lead Sponsor: National Cheng-Kung University Hospital

Brief Summary

While many studies have investigated the prognostic factors for patients undergoing surgical resection for primary brain tumors, decision-making for patients with brain metastasis (BM) is more complex because of their higher burden of comorbidities compared to those with primary brain tumors. In addition, although various prognostic indicators have been identified to predict prognosis in several types of cancer, such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), prognostic nutritional index (PNI), and systemic immune-inflammation index (SII), limited studies have yet determined which group of patients would yield beater survival outcome after surgical resection for BM. This study aimed to investigate the impact of patient and perioperative characteristics and prognostic indicators on survival outcome of patients undergoing surgical resection of BM.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-01-01
• Status Verified: 2024-02
• Study First Submitted: 2024-02-25
• Study First Submitted QC: 2024-03-18
• Study First Posted: 2024-03-19
• Last Update Submitted: 2024-03-20
• Last Update Posted: 2024-03-22
• Primary Completion: 2024-06-01
• Study Completion: 2024-09-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. patients with Clinical diagnosis of brain metastasis
2. patients who underwent craniotomy surgery for brain metastasis

Exclusion Criteria

1. patients with insufficient data for associated factors
2. patients who underwent stereotactic biopsy for brain metastasis
3. patients who did not undergo craniotomy surgery for brain metastasis

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Functional outcome of patients undergoing surgery for brain metastasis	from date of surgery until 6 months after surgery ordate of death from any cause, whichever came first	change of preoperative and postoperative modified rankin scale
survival outcome of patients undergoing surgery for brain metastasis	From date of surgery until the date of death from any cause, whichever came first, assessed up to 100 months	overall survival of patients

Trial Locations

Locations (1)

Jung-Shun Lee; 🇨🇳 Tainan, None Selected, Taiwan