Prognostic Factors in Epiretinal Membrane Surgery

Completed

• Conditions: Epiretinal Membranes

• Registration Number: NCT02406430
• Lead Sponsor: Centre Hospitalier Universitaire Dijon

Brief Summary

Retrospective interventional case series study reporting preoperative clinical and anatomical factors associated with visual recovery 1 year after combined cataract and idiopathic epiretinal membrane surgery. Age, duration of symptoms, and preoperative best corrected visual acuity appeared to be reliable prognostic factors. Combining these factors with analysis of the photoreceptors' inner and outer segments junction in spectral-domain optical coherence tomography provides a predictive score to estimate individual chances of good visual recovery

Detailed Description

Not available

Study Timeline

• Study Start: 2009-04
• Primary Completion: 2013-10
• Status Verified: 2015-03
• Study First Submitted: 2015-03-30
• Study First Submitted QC: 2015-03-30
• Last Update Submitted: 2015-03-30
• Study First Posted: 2015-04-02
• Last Update Posted: 2015-04-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 142

Inclusion Criteria

• symptomatic idiopathic epiretinal membrane operated on between April 2009 and September 2012 at the university hospital of Dijon, France.
• All patients signed informed consent for the surgical procedure.

Exclusion Criteria

• Patients were excluded if they presented any cause of secondary epiretinal membrane (including diabetic retinopathy, vein occlusion, ocular inflammation, retinal detachment, or previously vitrectomized eye), high myopia (axial length ≥ 26 mm or spherical equivalent ≥ 6 diopters), severe media opacities with weak SD-OCT signal strengths, or any macular or optic nerve disease. Patients with a follow-up of less than 12 months were excluded and only one eye was included in those with bilateral epiretinal membranes.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Best corrected visual acuity	1 year after the surgery	Best corrected visual acuity 1 year after the surgery, and preoperative factors associated with this visual outcome (age, duration of symptoms, initial best corrected visual acuity, and optical coherence tomography findings)

Secondary Outcome Measures

Name	Time	Method
To set up a predictive score for a >= 20/20 best corrected visual acuity	1 year after the surgery	To set up a predictive score for a \>= 20/20 best corrected visual acuity, 1year after a combined cataract and epiretinal membrane surgery