Predictive Value of Preoperative Evaluation in Cases of Recurrent Endometriosis

Recruiting

• Conditions: Endometriosis
• Interventions: Procedure: Surgery of endometriosis

• Registration Number: NCT06132009
• Lead Sponsor: Bagcilar Training and Research Hospital

Brief Summary

To investigate the effect of preoperative evaluation parameters in predicting recurrent disease in women who have undergone cystectomy or unilateral salpingo-oophorectomy due to endometriosis.

Detailed Description

Endometriosis is an estrogen-dependent gynecological disease characterized by the presence of endometrial-like tissue outside the uterine cavity, associated with pelvic pain and subfertility. Despite its benign character, endometriosis can recur after surgery and continues to be a disease that disrupts the quality of life of millions of women. This study aimed to examine the risk factors in women who underwent cystectomy or unilateral salpingo-oophorectomy due to endometriosis but had a recurrence. Therefore, the predictive value of parameters such as preoperative biochemical parameters, cyst size and the revised American Society for Reproductive Medicine (rASRM) Scoring system will be examined in recurrent cases.

Study Timeline

• Study Start: 2022-02-22
• Status Verified: 2023-11
• Study First Submitted: 2023-11-07
• Study First Submitted QC: 2023-11-13
• Last Update Submitted: 2023-11-13
• Study First Posted: 2023-11-15
• Last Update Posted: 2023-11-15
• Primary Completion: 2024-01-01
• Study Completion: 2024-02-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 64

Inclusion Criteria

• Women aged 18-50 who had a cystectomy or unilateral oophorectomy due to endometriosis

Exclusion Criteria

• Women who have had bilateral oophorectomy due to endometriosis
• Malignant conditions
• Smoking
• Women with autoimmune disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Recurrent group	Surgery of endometriosis	Group of women who underwent cystectomy or unilateral oophorectomy due to endometriosis but developed an endometrioma of at least 2 cm in size in a single ovary during follow-up.
Remission group	Surgery of endometriosis	Group of women who underwent cystectomy or unilateral oophorectomy due to endometriosis but were in remission during follow-up

Primary Outcome Measures

Name	Time	Method
Prediction of endometriosis recurrence	6-180 months	Which women are more likely to have recurrence after endometriosis surgery?

Trial Locations

Locations (1)

Bagcilar Teaching and Research Hospital; 🇹🇷 Istanbul, Bagcilar, Turkey