AGREEMENT OF RENAL FUNCTION ESTIMATION BY DIFFERENT ESTIMATED GLOMERULAR FILTRATION RATE EQUATIONS FOR DETERMINATION OF NON-VITAMIN K ORAL ANTICOAGULANT DOSAGE

• Conditions: OACs dose adjustment according to eGFR from different equations; NOACs; dosage adjustment; eGFR equations; renal impairment

• Registration Number: TCTR20220430001
• Lead Sponsor: Faculty of Pharmaceutical Sciences, Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-04-30
• Study Completion: 2022-09-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 1062

Inclusion Criteria

1. Patients who was 18-year-old or older.

2. Patients who received NOACs from out-patient clinic in King Chulalongkorn Memorial Hospital during January 1st - December 31st, 2021.

Exclusion Criteria

1. Patients with incomplete medical records for eGFR calculation.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
eGFR cross-sectional ICC

Secondary Outcome Measures

Name	Time	Method
dose recommendation cross-sectional CCC, Bland-Altman plot, weight kappa, percent discordance,dose recommendation in elderly cross-sectional CCC, Bland-Altman plot, weight kappa, percent discordance