Strengthening the weakness of the lower esophageal sphincter leads to reflux with stem cells derived from human adipose tissue.

Phase 1

Recruiting

• Conditions: K21.9; Gastroesophageal reflux.; Oesophageal reflux NOS

• Registration Number: IRCT20181113041635N2
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Age of 18 to 60 years
Without hiatal herniation
Without barretts esophagus
Without chronic disease
Without pregnancy
Without morbidly obese
Gastroesophageal reflux
Proven weakness of the lower esophageal sphincter

Exclusion Criteria

Those who are very old and it is difficult to get data from them
Individuals with chronic illnesses, such as heart or kidney failure, and it is difficult to get data from them
Individuals with congenital esophageal disorders
Individuals who participated in a clinical trial within the last 6 months
Those who have severe weight gain and it is difficult to get data from them
Individuals who do not have personal consent to participate in the study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Esophageal sphincter pressure. Timepoint: At the beginning of the study (before the intervention), the first week after the intervention, the second week after the intervention, the first month after the intervention, the third month after the intervention and the sixth month after the intervention. Method of measurement: manometry.