A study to compare two drugs Dexmedetomidine and Lignocaine to bring down blood pressure, pulse rate, respiratory rate and airway response to endotracheal extubation after CABG(Coronary Artery Bypass Graft) surgery.
Not yet recruiting
- Conditions
- Chronic ischemic heart disease, unspecified, (2) ICD-10 Condition: O||Medical and Surgical,
- Registration Number
- CTRI/2021/07/034534
- Lead Sponsor
- INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES PATNA
- Brief Summary
The purpose of study is to compare the efficacy of Dexmedetomidine and lignocaine to attenuate(decrease)the hemodynamic and airway response to endotracheal extubation in elective post operative CABG (coronary artery bypass graft) Surgery
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
(1)ASA 2 and 3 (2)Patient undergoing elective CABG Surgery (3)Mallampati grade 1 and 2.
Exclusion Criteria
(1)Allergy to studied drug (2)Patient with significant valvular heart disease (3)Patient with significant bradycardia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the hemodynamic parameter and airway response 1,3,5,7 minutes after drug administration | 1,3,5,10,15,20 minutes after extubation
- Secondary Outcome Measures
Name Time Method To assess sedation status of patient and Airway response in form of coughing brochospadm and laryngospasm At extubation and 1,3,5,10,15,20 minutes after extubation
Trial Locations
- Locations (1)
CTVS complex, INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCE PATNA
🇮🇳Patna, BIHAR, India
CTVS complex, INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCE PATNA🇮🇳Patna, BIHAR, IndiaDR MITHILESH KUMARPrincipal investigator7979822440mithileshpmc2k10@gmail.com