The effect of the drug dexmedetomidine in nebulized form in bronchoscopy as a pre-medicatio
Not Applicable
- Conditions
- Health Condition 1: J470- Bronchiectasis with acute lower respiratory infection
- Registration Number
- CTRI/2022/03/040799
- Lead Sponsor
- Kasturba Medical college
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients in the age group 18 to 65 years undergoing flexible bronchoscopy in the Department of Respiratory Medicine.
Exclusion Criteria
a.Patients with known or suspected allergy to lignocaine or Dexmedetomidine
b.Patients with renal or hepatic insufficiency
c.Patients with seizure disorder
d.COPD patients with FEV1 <50%
e.Patients with psychiatric disorder
f.Hemodynamically unstable patients including cardiac failure
g.Heart rate <50 beats per min or second or third degree heart block
h.Patients with body weight more than 70kg.
i.Pregnancy and lactation
j.Patients posted for bronchoscopy and not consenting for study.
h. Patients with nasal abnormalitues/infectionn
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Composite score during the bronchoscopy procedure. <br/ ><br>2.Numerical Rating Scale (NRS) for pain intensity and distress. <br/ ><br>3.Visual Analogue Scale (VAS) for cough. <br/ ><br>4.Ramsay sedation score (RSS). <br/ ><br>5.Ease of bronchoscopy procedure as assessed by Observer B <br/ ><br>Timepoint: Primary outcomes will be assessed during bronchoscopy and at the end of bronchoscopy. <br/ ><br>Secondary parameters like vital parameters will be assessed at baseline, at the start of the procedure, 5 minutes into the procedure, 10 minutes, at the end of scopy and 10 minutes post procedure. <br/ ><br>Patient is assessed 2 hours post procedure for other variables. <br/ ><br>Theres no follow up required for the study.
- Secondary Outcome Measures
Name Time Method 1.Willingness for repeatability of the procedure as felt by patient. <br/ ><br>2.Variations in heart rate (HR), blood pressure (BP), oxygen saturation (SpO2). <br/ ><br>3.Duration of bronchoscopy procedure <br/ ><br>4.Procedures underwent during bronchoscopy (Bronchial washing, broncho-alveolar lavage (BAL), bronchial brushing, endobronchial biopsy, transbronchial needle aspiration (TBNA), or transbronchial lung biopsy (TBLB)Timepoint: 0,1year