Comparing Effects of Recruitment Maneuver on Functional Residual Capacity in Patients Undergo Laparoscopic Surgery : A Randomized Prospective Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Comparison of FRC measurements at beginning and end of anesthesia
研究概览
简要总结
Recruitment maneuver is frequently used in daily anaesthesia routine to prevent athelectasia and ventilation perfusion mismatch. Especially pneumoperitoneum in laparoscopic surgeries affects the functional residual capacity (FRC) negatively. Recently, FRC can be measured at bedside in intensive care units.
The lack of studies evaluating FRC measurements peroperatively and how recruitment maneuvers affect it, attract attention.
详细描述
An ICU-ventilator capable to measure the FRC will be used for the mechanical ventilation in patients undergıoing laparoscopic surgery, where anaesthesia maintenance will be achieved with TIVA.
FRC will be measured in different steps of the operation. In the study group, a recruitment manover will be applied to evaluate its effects on FRC.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1-18-65 years age 2-no lung disease 3-laparoscopic cholecystectomies surgery
排除标准
- •<18 years old
- •>65 years old
- •denial of patient
- •patients having one of: lung disease, cardiac failure, severe cardiac valvular disease
研究组 & 干预措施
control group
3 FRC measurements will be perforemed, whereby : First measurement; after aneshesia induction and intubation. Second measurement; after pneumoperitoneum Third measurement; end of the operation
After the operation,Postoperative Room Air Test (RAT) will be applied.
study group
5 FRC measurements will be performed We will apply recruitment maneuver two times to patients with 30cmH2O pressure for 15 seconds .
First Recruitment maneuver will be applied after the fşrst measurement of FRC following intubation Second Recuitment maneuver will be applied at the end of operation
First FRC measurement after anesthesia induction and intubation. Second FRC measurement after first recruitment maneuver Third FRC measurement; after pneumoperitoneum Fourth FRC measurement before second recruitment maneuver Fifth FRC measurement after second recruitment maneuver and at the end of operation
干预措施: recruitment maneuver (Procedure)
结局指标
主要结局
Comparison of FRC measurements at beginning and end of anesthesia
时间窗: within max 5 minutes after the intubation and with max 5 minutes before the extubation
First FRC will be measured after ; the last FRC will be measure bedore the extubation
次要结局
- Positive room air test(in recovery room 30 minutes after operation)
研究者
Nuzhet Mert Senturk, MD, Prof
Prof.Dr.
Istanbul University