The Valve of Hyaluronic Binding Selection (PICSI) in Improving IVF Outcome
- Conditions
- Infertility
- Registration Number
- NCT01916213
- Lead Sponsor
- St. Luke's-Roosevelt Hospital Center
- Brief Summary
The investigators would like to assess whether selecting mature sperm using PICSI (selecting for sperm that bind hyaluronan) can optimize the IVF outcome of ICSI .
Aim
1. Primary outcome: To compare routine sperm selection using ICSI with sperm selection using PICSI plates in terms of implantation and fertilization rates for couples with male factor fertility
2. Secondary outcome : To compare live birth rates ,ongoing pregnancies and miscarriage rates for couples with male factor infertility using routine sperm selection with ICSI compared to using PICSI plates for sperm selection
Hypothesis:
Sperm selected for ICSI using (PICSI) will reveal increased implantation rates in comparison to sperm selected for conventional ICSI
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 30
- In order to participate in the study women must be 42 years old or younger and suffer from male factor infertility however they may have other causes for their infertility
- male factor infertility as defined by one or more of the following sperm parameters: <20 Million /ml sperm concentration < 30% normal morphology < 3% Kruger morphology < 50% motility sion Criteria:
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method implantation rate 12 months
- Secondary Outcome Measures
Name Time Method fertilization rate 12 months
Trial Locations
- Locations (1)
Continuum Reproductive Center
🇺🇸New york, New York, United States
Continuum Reproductive Center🇺🇸New york, New York, United States