Effectiveness of vitamin D supplementation on severity of chronic liver disease
Phase 2
- Conditions
- Chronic liver disease.Chronic passive congestion of liver
- Registration Number
- IRCT2016020326342N1
- Lead Sponsor
- Vice Chancellor for Research, Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
All the decompensated cirrhosis patients (CHILD=7) admitted to hospital or referred to Gastroenterology Clinics; aged more than 18 years; and consent to participate in the study.
Exclusion criteria: Human immunodeficiency virus patients; renal failure due to reasons other than liver failure; malabsorption such as chronic diarrhea, celiac, chronic pancreatitis; patients undergoing corticosteroid treatment; pregnancy; and cirrhosis patients secondary to cholestasis such as primary biliary cirrhosis
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method iver function. Timepoint: 3 months after intervention. Method of measurement: MELD scoring system; according to levels of bilirubin and creatinine serum.
- Secondary Outcome Measures
Name Time Method iver function. Timepoint: 3 months after intervention. Method of measurement: Child-Pugh scoring system; classifies the severity of liver diseases into five categories.