The efficacy of Vitamin D supplementation in the treatment of schizophrenia
Phase 1
- Conditions
- Schizophrenia.Schizophrenia
- Registration Number
- IRCT201507087373N5
- Lead Sponsor
- Vice chancer for research , Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
diagnosis of schizophrenia according to DSM-5 criteria ,age range 18-68 ,a score of at least 60 in PANSS
Exclusion criteria:Mental Retardation; Organic brain disease; Parathyroid disorders; Use of Vitamin D Supplementation in recent 3 months; Pregnancy and Lactation; Vitamin D metabolism disorders; serum level of Vitamin D below 10 nmol/ml; serum level of Vitamin D over 100 nmol/ml; No interest to continue treatment; substance abuse; GFR below 60 ml/min; No response to previous treatment with Olanzapin; BMI over 30
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Positive and Negative Syndrome Scale(PANSS). Timepoint: Before intervention and every one month for 3 months. Method of measurement: Clinical Examination.
- Secondary Outcome Measures
Name Time Method Extrapyramidal side effects. Timepoint: before intervention and every one month for 3 months. Method of measurement: clinical exam.