Efficacy of Various Aerobic Exercises on Abdominal Obesity in Women With Metabolic Syndrome.
- Conditions
- Metabolic Syndrome
- Interventions
- Other: Supervised treadmill group (%50 VO2 max) (group 2)Device: ECE PEDO pedometer group (%50 VO2 max) (group 3)Other: Supervised treadmill group (%70 VO2 max) (group 1)
- Registration Number
- NCT03445741
- Lead Sponsor
- Pamukkale University
- Brief Summary
Objective: To show metabolic and hormonal responses and effects on abdominal obesity of aerobic exercise in different intensity and duration and detraining period in women with metabolic syndrome.
- Detailed Description
Objective: To show metabolic and hormonal responses and effects on abdominal obesity of aerobic exercise in different intensity and duration and detraining period in women with metabolic syndrome.
Methods: Fifty-one women with metabolic syndrome were divided into three groups: 12 weekly sessions of high intensity supervised treadmill group, respectively, at % 70 of maximum oxygen consumption (group I, n=17), low intensity supervised treadmill group, respectively at % 50 of maximum oxygen consumption (group II, n=17) and walking at low intensity, respectively at % 50 of maximum oxygen consumption with ECEPEDO pedometer (group III, n=17). Target heart rate (HR) corresponding to values of 50-70 % VO2max were determined by the submaximal treadmill test. Group 1 and 2 were instructed walking at their target HR on a treadmill. The number of steps taken in a minute corresponding to target HR was determined by a criterion pedometer and group 3 was instructed walking in this step range recorded to ECE PEDO giving audible feedback. Participants were evaluated by weight, BMI, waist circumference (WC), blood sugar, LDL, HDL and triglyceride; viseral fat, trunk fat and waist circumference by bioelectrical impedance device (VIScan); ergospirometric VO2max at baseline, 12-week and 4-week detraining period.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 60
- eligible participants who meet the criteria for inclusion were women with metabolic syndrome diagnosis according to National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria and were 25-65 years old.
- Participants were well communicative, motivated and willing to participate in the study.
- The exclusion criteria were presence of uncontrolled hypertension, type 2 diabetes mellitus, atherosclerotic heart disease, using drugs to affect thyroid, lipids metabolism and insulin sensitization, musculoskeletal or systemic diseases contradicting the exercise, a neurological or psychiatric disease affecting cooperation and cognitive function.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Supervised treadmill group (%50 VO2 max) Supervised treadmill group (%50 VO2 max) (group 2) Supervised treadmill group (%50 VO2 max) (group 2): The participants were instructed walking exercise at their target heart rate, (% 50 of maximum oxygen consumption) on a treadmill in Sports Rehabilitation Unit of Pamukkale University. ECE PEDO pedometer group (%50 VO2 max) ECE PEDO pedometer group (%50 VO2 max) (group 3) ECE PEDO pedometer group (%50 VO2 max) (group 3): The participants were instructed walking with ECE PEDO which the number of steps taken in a minute corresponding to target HR at % 50 of maximum oxygen consumption were provided. Supervised treadmill group (%70 VO2 max) Supervised treadmill group (%70 VO2 max) (group 1) Supervised treadmill group (%70 VO2 max) (group 1): The participants were instructed walking exercise at their target heart rate, (% 70 of maximum oxygen consumption) on a treadmill in Sports Rehabilitation Unit of Pamukkale University.
- Primary Outcome Measures
Name Time Method *Change from baseline in weight (kilograms) at week 12 and 4- week detraining period. Week 12 and week 16 Weight was measured with weight scale.
*Change from baseline in free fatty acide parameter at week 12 and 4- week detraining period. Week 12 and week 16 Fasting blood samples were collected at morning hours before exercise testing. To perform free fatty acide values, a sum of blood were stored at -80 C for later study.
*Change from baseline in abdominal viseral fat and trunk fat and measured by VIScan at week 12 and 4-week detraining period. Week 12 and week 16 BIA device ViScan, designed to estimate visceral adiposity and trunk fat percentage. A wireless 'electrode belt' is placed on the bare midriff of the subject in supine position. The belt then uses dual frequency bio impedance (6.25 and 50 kHz) to measure trunk and visceral fat resistance and transmit the readings via infrared to the base unit.
*Change from baseline in noradrenaline parameter at week 12 and 4- week detraining period. Week 12 and week 16 Fasting blood samples were collected at morning hours before exercise testing. To perform noradrenaline values, a sum of blood were stored at -80 C for later study.
*Change from baseline in Epinephrine/Adrenaline parameter at week 12 and 4- week detraining period. Week 12 and week 16 Fasting blood samples were collected at morning hours before exercise testing. To perform adrenaline values, a sum of blood were stored at -80 C for later study.
*Change from baseline in oxyntomodulin parameter at week 12 and 4- week detraining period. Week 12 and week 16 Fasting blood samples were collected at morning hours before exercise testing. To perform oxyntomodulin values, a sum of blood were stored at -80 C for later study.
*Change from baseline in glycerol parameter at week 12 and 4- week detraining period. Week 12 and week 16 Fasting blood samples were collected at morning hours before exercise testing. To perform glycerol values, a sum of blood were stored at -80 C for later study.
- Secondary Outcome Measures
Name Time Method