NCT01267786Unknown4 期
The Effect of Volatile Anesthetics Sevoflurane and Desflurane on Liver, Renal and Cardiovascular Systems During Liver Surgery
Aretaieio Hospital2 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2010年12月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Oxidotic stress after hepatectomy.
研究概览
简要总结
The aim of the study is to investigate the effect of sevoflurane and desflurane on hepatic function after ischemic/reperfusion injury and the sequence influence on renal and cardiovascular systems.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing liver surgery
排除标准
- •ASA IV, Cardiovascular diseases
结局指标
主要结局
Oxidotic stress after hepatectomy.
时间窗: 5 d postop.
Perioperative liver and renal biopsies and follow up with liver renal function tests plus intraoperative and postoperative cardiovascular monitoring
次要结局
- Liver and renal dysfunction(5 d)
研究者
研究点 (2)
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