CTRI/2025/11/097157尚未招募不适用
Developing Predictive Models for Classifying Infection vs. Malignancy in PET/CT Imaging of Lung, Head and Neck, and Breast Cancer
Manipal Institute of Technology1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2025年12月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Improved diagnostic precision in differentiating infection from malignancy
研究概览
简要总结
This study aims to develop a hybrid predictive model to differentiate infection from malignancy using clinical data, radiomic features, and PET CT metabolic parameters. A comprehensive dataset will be collected, preprocessed, and analyzed. Machine learning methods will be used to identify key features and build a diagnostic model. The performance of the model will be validated and its ability to improve diagnostic accuracy and clinical decision making will be assessed across lung, breast, and head and neck cancer cases.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)(—)
- 性别
- All
入选标准
- •Histopathologically confirmed cases (via biopsy or FNAC) of carcinoma of the lung, breast, or head and neck.
- •Patients undergoing 18F-FDG PET/CT imaging for: Staging or restaging of malignancy; Evaluation of Pyrexia of Unknown Origin (PUO) and/or suspected infectious pathology; Assessment of imaging heterogeneity in known malignancies;
- •Availability of complete PET/CT imaging data in DICOM format
- •Availability of relevant clinical records.
排除标准
- •Incomplete or poor-quality PET/CT imaging
- •Missing or inadequate clinical data
- •Pregnant women and lactating women.
结局指标
主要结局
Improved diagnostic precision in differentiating infection from malignancy
时间窗: 3 years
次要结局
未报告次要终点
研究者
Sandra Sony
Manipal Institute of Technology
研究点 (1)
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